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Juhani
Knuuti
Director, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Increased B-type natriuretic Peptide concentration is associated with reduced coronary vasoreactivity in patients with dilated cardiomyopathy but not in healthy young subjects. (2011)
ISRN Cardiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
The Effect Of Nitric Oxide Synthase Inhibition On Exchange Of Glucose And Free Fatty Acids In Human Skeletal Muscle (2011)
Medicine and Science in Sports and Exercise
(O2 Muu julkaisu )
Uptake of 68gallium in atherosclerotic plaques in LDLR-/- ApoB100/100 mice (2011)
EJNMMI Research
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Coronary plaque imaging in patients with unstable angina pectoris using dual gated [18F]-FDG PET/CT (2011)
European Heart Journal Supplements
(O2 Muu julkaisu )
Intrapericardial, But Not Extrapericardial, Fat Is an Independent Predictor of Impaired Hyperemic Coronary Perfusion in Coronary Artery Disease (2011)
Arteriosclerosis, Thrombosis, and Vascular Biology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). (2011)
European Heart Journal
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Hybrid cardiac imaging: SPECT/CT and PET/CT. A joint position statement by the European Association of Nuclear Medicine (EANM), the European Society of Cardiac Radiology (ESCR) and the European Council of Nuclear Cardiology (ECNC). (2011)
European Journal of Nuclear Medicine and Molecular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Myocardial Perfusion Single Photon Emission Computed Tomography and Positron Emission Tomography. (2011)
(Kirjan tai muun kokoomateoksen osa (B2))Cold Pressor Test Safety-The Incidence of Vasovagal Reactions (2011)
American Journal of Cardiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Simultaneous estimation of blood flow and oxygen consumption in human myocardium by 1-tissue compartment model for [11-C]Acetate study (2011)
EJNM, European Journal of Nuclear Medicine and Molecular Imaging
(O2 Muu julkaisu )