Juhani
Knuuti
Director, Turku PET Centre
Professor, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
ESC Guidelines for the Management of Acute Myocardial Infarction in Patients Presenting With ST-Segment Elevation Guía de práctica clínica de la ESC para el manejo del infarto agudo de miocardio en pacientes con elevación del segmento ST: Grupo de Trabajo para el manejo del infarto agudo de miocardio con elevación del segmento ST de la Sociedad Europea de Cardiología (ESC) (2013)
Revista Española de Cardiología
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Interobserver reproducibility of myocardial perfusion quantification with N-13-ammonia and Rb-82 PET studied with Carimas (2013)
European Journal of Nuclear Medicine and Molecular Imaging
(O2 Muu julkaisu )
Gene transfer using vammin induces robust angiogenesis and increases ejection fraction in ischemic porcine myocardium (2013)
European Heart Journal
(O2 Muu julkaisu )
Anatomic Versus Physiologic Assessment of Coronary Artery Disease: Role of coronary flow reserve, fractional flow reserve, and positron emission tomography imaging in revascularization decision-making (2013)
Journal of the American College of Cardiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Validation of [F-18]fluorodeoxyglucose and positron emission tomography (PET) for the measurement of intestinal metabolism in pigs, and evidence of intestinal insulin resistance in patients with morbid obesity (2013)
Diabetologia
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Pulmonary blood flow and its distribution in highly trained endurance athletes and healthy control subjects (2013)
Journal of Applied Physiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Effect of nitric oxide synthase inhibition on the exchange of glucose and fatty acids in human skeletal muscle. (2013)
Nutrition and Metabolism
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Project AQUA: towards standardization of software tools for myocardial perfusion quantification with O-15-water PET (2013)
European Journal of Nuclear Medicine and Molecular Imaging
(O2 Muu julkaisu )
Regulation of subcutaneous adipose tissue blood flow during exercise in humans (2013)
Journal of Vascular Research
(O2 Muu julkaisu )
Is cardiac magnetic resonance imaging causing DNA damage? (2013)
European Heart Journal
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))