Juhani
Knuuti
Director, Turku PET Centre
Professor, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Molecular Imaging of Heart Failure : An Update and Future Trends (2024)
Seminars in Nuclear Medicine
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä)
Location-specific prognostic significance of plaque burden, stenosis, and plaque morphology in coronary artery disease (2024)
EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Clinical risk prediction, coronary computed tomography angiography, and cardiovascular events in new-onset chest pain: the PROMISE and SCOT-HEART trials (2024)
European Heart Journal
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Smartphone-Based Recognition of Heart Failure by Means of Microelectromechanical Sensors (2024)
JACC: Heart Failure
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Impact of Absolute Myocardial Blood Flow Quantification on the Diagnostic Performance of PET-Based Perfusion Scans Using 82Rubidium (2024)
Circulation: Cardiovascular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial (2024)
JAMA Cardiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Effects of reduced sedentary time on resting, exercise and post-exercise blood pressure in inactive adults with metabolic syndrome – a six-month exploratory RCT (2024)
Journal of Human Hypertension
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Explainable deep-learning-based ischemia detection using hybrid O-15 H2O perfusion positron emission tomography and computed tomography imaging with clinical data (2024)
Journal of Nuclear Cardiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Diagnostic Performance of Quantitative Perfusion Cardiac Magnetic Resonance Imaging in Patients with Prior Coronary Artery Disease (2024)
EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Natural History of Myocardial αvβ3 Integrin Expression After Acute Myocardial Infarction : Correlation with Changes in Myocardial Blood Flow (2024)
Journal of Nuclear Medicine
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )