Juhani Knuuti profile picture
Juhani
Knuuti
Director, Turku PET Centre
Professor, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging

Contact

+358 29 450 2345
+358 50 059 2998
Kiinamyllynkatu 4-8
20520
Turku

Biography

Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.

Publications

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Tiredness after work associates with less leisure-time physical activity (2024)

Scientific Reports
Sjöros Tanja, Norha Jooa, Johansson Riitta, Laine Saara, Garthwaite Taru, Vähä-Ypyä Henri, Löyttyniemi Eliisa, Kalliokoski Kari K., Sievänen Harri, Vasankari Tommi, Knuuti Juhani, Heinonen Ilkka H. A.
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

The effectiveness of coronary computed tomography angiography and functional testing for the diagnosis of obstructive coronary artery disease: results from the individual patient data Collaborative Meta-Analysis of Cardiac CT (COME-CCT) (2024)

Insights into imaging
Schlattmann, Peter; Wieske, Viktoria; Bressem, Keno K.; Götz, Theresa; Schuetz Georg M.; Andreini, Daniele; Pontone, Gianluca; Alkadhi, Hatem; Hausleiter, Jörg; Zimmermann, Elke; Gerber, Bernhard; Shabestari, Abbas A.; Meijs, Matthijs F.L.; Sato, Akira; Øvrehus, Kristian A.; Jenkins, Shona M. M.; Knuuti, Juhani; Hamdan, Ashraf; Halvorsen, Björn A.; Mendoza-Rodriguez, Vladimir; Rixe, Johannes; Wan, Yung-Lian; Langer, Christoph; Leschka, Sebastian; Martuscelli, Eugenio; Ghostine, Said; Tardif, Jean-Claide; Sánchez, Alejandra Rodriguez; Haase, Robert; Dewey, Marc
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Location-specific prognostic significance of plaque burden, stenosis, and plaque morphology in coronary artery disease (2024)

EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
Jukema, Ruurt A; Maaniitty, Teemu; Nurmohamed, Nick S; Raijmakers, Pieter G; Planken, R Nils; Twisk, Jos; van der Harst, Pim; Cramer, Maarten J; Min, James K; Earls, James P; Knaapen, Paul; Saraste, Antti; Knuuti, Juhani; Danad, Ibrahim
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Impact of Absolute Myocardial Blood Flow Quantification on the Diagnostic Performance of PET-Based Perfusion Scans Using 82Rubidium (2024)

Circulation: Cardiovascular Imaging
Rasmussen, Laust Dupont; Gormsen, Lars Christian; Ejlersen, June Anita; Karim, Salma Raghad; Westra, Jelmer; Knudsen, Lars Lyhne; Kirk, Jane; Søndergaard, Hanne Maare; Mortensen, Jesper; Knuuti, Juhani; Christiansen, Evald H.; Eftekhari, Ashkan; Bøttcher, Morten; Winther, Simon
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial (2024)

JAMA Cardiology
DISCHARGE Trial Group, Bosserdt M, Serna-Higuita LM, Feuchtner G, Merkely B, Kofoed KF, Benedek T, Donnelly P, Rodriguez-Palomares J, Erglis A, Štechovský C, Šakalyte G, Adic NC, Gutberlet M, Dodd JD, Diez I, Davis G, Zimmermann E, Kepka C, Vidakovic R, Francone M, Ilnicka-Suckiel M, Plank F, Knuuti J, Faria R, Schröder S, Berry C, Saba L, Ruzsics B, Rieckmann N, Kubiak C, Hansen KS, Müller-Nordhorn J, Szilveszter B, Sigvardsen PE, Benedek I, Orr C, Valente FX, Zvaigzne L, Suchánek V, Jankauskas A, Adic F, Woinke M, Hensey M, Lecumberri I, Thwaite E, Laule M, Kruk M, Neskovic AN, Mancone M, Kusmierz D, Pietilä M, Ribeiro VG, Drosch T, Delles C, Porcu M, Fisher M, Boussoussou M, Kragelund C, Aurelian R, Kelly S, Garcia Del Blanco B, Rubio A, Maurovich-Horvat P, Hove JD, Rodean I, Regan S, Cuellar-Calabria H, Molnár L, Larsen L, Hodas R, Napp AE, Haase R, Feger S, Mohamed M, Neumann K, Dreger H, Rief M, Wieske V, Estrella M, Martus P, Sox HC, Dewey M
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Effects of reduced sedentary time on resting, exercise and post-exercise blood pressure in inactive adults with metabolic syndrome – a six-month exploratory RCT (2024)

Journal of Human Hypertension
Norha Jooa, Sjöros Tanja, Garthwaite Taru, Laine Saara, Saarenhovi Maria, Kallio Petri, Laitinen Kirsi, Houttu Noora, Vähä-Ypyä Henri, Sievänen Harri, Löyttyniemi Eliisa, Vasankari Tommi, Knuuti Juhani, Kalliokoski Kari K., Heinonen Ilkka H. A.
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )