Juhani
Knuuti
Director, Turku PET Centre
Professor, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Preclinical evaluation of [18F]SYN1 and [18F]SYN2, novel radiotracers for PET myocardial perfusion imaging (2024)
EJNMMI Research
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Tiredness after work associates with less leisure-time physical activity (2024)
Scientific Reports
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
The effectiveness of coronary computed tomography angiography and functional testing for the diagnosis of obstructive coronary artery disease: results from the individual patient data Collaborative Meta-Analysis of Cardiac CT (COME-CCT) (2024)
Insights into imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Molecular Imaging of Heart Failure : An Update and Future Trends (2024)
Seminars in Nuclear Medicine
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä)
Location-specific prognostic significance of plaque burden, stenosis, and plaque morphology in coronary artery disease (2024)
EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Smartphone-Based Recognition of Heart Failure by Means of Microelectromechanical Sensors (2024)
JACC: Heart Failure
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Impact of Absolute Myocardial Blood Flow Quantification on the Diagnostic Performance of PET-Based Perfusion Scans Using 82Rubidium (2024)
Circulation: Cardiovascular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Clinical risk prediction, coronary computed tomography angiography, and cardiovascular events in new-onset chest pain: the PROMISE and SCOT-HEART trials (2024)
European Heart Journal
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Age and Computed Tomography and Invasive Coronary Angiography in Stable Chest Pain: A Prespecified Secondary Analysis of the DISCHARGE Randomized Clinical Trial (2024)
JAMA Cardiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Effects of reduced sedentary time on resting, exercise and post-exercise blood pressure in inactive adults with metabolic syndrome – a six-month exploratory RCT (2024)
Journal of Human Hypertension
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )