Juhani
Knuuti
Director, Turku PET Centre
Professor, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Myocardial Blood Flow in Newly Diagnosed Breast Cancer Patients at Rest and During Exercise (2024)
American Physiology Summit, Physiology
(Abstrakti)
Prognostic value of a novel artificial intelligence-based coronary CTA-derived ischemia algorithm among patients with normal or abnormal myocardial perfusion (2024)
Journal of Cardiovascular Computed Tomography
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Value of Ischemia in Prognosis and Guiding Revascularization Among Patients With Chronic Coronary Artery Disease (2024)
Circulation: Cardiovascular Imaging
(B1 Vertaisarvioitu muu artikkeli (esim. pääkirjoitus, letter, comment) tieteellisessä lehdessä)
Effect of Body Mass Index on Effectiveness of CT versus Invasive Coronary Angiography in Stable Chest Pain: The DISCHARGE Trial (2024)
Radiology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Daily standing time, dietary fiber, and intake of unsaturated fatty acids are beneficially associated with hepatic insulin sensitivity in adults with metabolic syndrome (2024)
Frontiers in Endocrinology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Clinical development and proof of principle testing of new regenerative vascular endothelial growth factor-D therapy for refractory angina: rationale and design of the phase 2 ReGenHeart trial (2024)
Open Heart
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Plasma lipidomics and coronary plaque changes: a substudy of the SMARTool clinical trial (2024)
EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
The effects of myocardial bridging on two-dimensional myocardial strain during dobutamine stress echocardiography (2024)
International Journal of Cardiovascular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Calcium Scoring Improves Clinical Management in Patients With Low Clinical Likelihood of Coronary Artery Disease (2024)
JACC: Cardiovascular Imaging
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Polygenic Risk Scores in Predicting Coronary Artery Disease in Symptomatic Patients. A Validation Study (2024)
Journal of Atherosclerosis and Thrombosis
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )