Juhani
Knuuti
Director, Turku PET Centre
Professor, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Clinical Value of Absolute Quantification of Myocardial Perfusion With O-15-Water in Coronary Artery Disease (2011)
Circulation: Cardiovascular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Effects of Age, Diet, and Type 2 Diabetes on the Development and FDG Uptake of Atherosclerotic Plaques (2011)
JACC: Cardiovascular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
ESC Guidelines on the management of cardiovascular diseases during pregnancy: the Task Force on the Management of Cardiovascular Diseases during Pregnancy of the European Society of Cardiology (ESC). (2011)
European Heart Journal
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Metabolic remodelling in human heart failure (2011)
Cardiovascular Research
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Simultaneous estimation of blood flow and oxygen consumption in human myocardium by 1-tissue compartment model for [11-C]Acetate study (2011)
EJNM, European Journal of Nuclear Medicine and Molecular Imaging
(O2 Muu julkaisu )
Intrapericardial, But Not Extrapericardial, Fat Is an Independent Predictor of Impaired Hyperemic Coronary Perfusion in Coronary Artery Disease (2011)
Arteriosclerosis, Thrombosis, and Vascular Biology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC). (2011)
European Heart Journal
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Increased B-type natriuretic Peptide concentration is associated with reduced coronary vasoreactivity in patients with dilated cardiomyopathy but not in healthy young subjects. (2011)
ISRN Cardiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Skeletal muscle blood flow and oxygen uptake at rest and during exercise in humans: a pet study with nitric oxide and cyclooxygenase inhibition (2011)
AJP - Regulatory, Integrative and Comparative Physiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Cardiac computed tomography and myocardial perfusion scintigraphy for risk stratification in asymptomatic individuals without known cardiovascular disease: A position statement of the Working Group on Nuclear Cardiology and Cardiac CT of the European Society of Cardiology. (2011)
European Heart Journal
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))