Jaana Vuopio profile picture
Jaana
Vuopio
Senior Advisor, Institute of Biomedicine
Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology

Contact

Kiinamyllynkatu 10
20520
Turku

Areas of expertise

• Bacterial infections and asymptomatic carriage caused by beta-hemolytic streptococci
genomic evolution of the bacterium
host susceptibility and risk factors to these infections.
• Molecular epidemiology
surveillance and prevention of spread of antimicrobial resistant bacteria in humans
• Diagnostics and genomic characterization of bacterial pathogens

Research

Bacterial infections cause a significant disease burden in humans. We know that the disease spectrum can vary from asymptomatic carriage to life threatening infections.

Our aim is to gain understanding on reasons why certain individuals develop a disease and the others do not, why pathogens spread and cause epidemics and what could be the means to prevent this from happening. My long standing research interest has also resided in antimicrobial resistance, especially in molecular epidemiology and spread of MRSA, VRE and ESBL-producing Enterobacteriaceae both in health care setting and community.

Our current research areas cover:

  • Invasive Group A streptococcal disease
  • Molecular epidemiology and disease burden of Group A streptococcal infections
  • Molecular epidemiology and spread of MRSA
  • Surveillance of AMR

Research group members:

  • Kirsi Gröndahl-Yli-Hannuksela, Ph.D., Adjunct professor, University teacher
  • Johanna Vilhonen, M.D., Ph.D., specialist in IDs
  • Tiina Hirvioja, M.D., Ph.D. fellow, specialist in IDs
  • Jaakko Silvola, M.D., Ph.D. fellow
  • Ville Kaila, M.D., Ph.D. fellow, specialist in IDs (based at Tampere University Hospital, Tampere)
  • Erastus Haindongo, M.Sc., Ph.D. fellow (based at University of Namibia, Windhoek)
  • Laura Lindholm, M.Sc., Ph.D. fellow (based at Finnish Institute of Health and Welfare)



Publications

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Combined interventions are effective in MRSA control. (2015)

Infectious Diseases
Elina Jokinen, Janne Laine , Reetta Huttunen, Pertti Arvola, Jaana Vuopio, Laura Lindholm, Risto Vuento, Jaana Syrjänen
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Evolutionary pathway to increased virulence and epidemic group A Streptococcus disease derived from 3,615 genome sequences. (2014)

Proceedings of the National Academy of Sciences of the United States of America
Waleed Nasser, Stephen B. Beres, Randall J. Olsen, Melissa A. Dean, Kelsey A. Rice, S. Wesley Long, Karl G. Kristinsson, Magnus Gottfredsson, Jaana Vuopio, Kati Raisanen, Dominique A. Caugant, Martin Steinbakk, Donald E. Low, Allison McGeer, Jessica Darenberg, Birgitta Henriques-Normark, Chris A. Van Beneden, Steen Hoffmann, James M. Musser
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Origin and evolution of European community-acquired methicillin-resistant Staphylococcus aureus. (2014)

mBio
Stegger M, Wirth T, Andersen PS, Skov RL, De Grassi A, Simões PM, Tristan A, Petersen A, Aziz M, Kiil K, Cirković I, Udo EE, del Campo R, Vuopio-Varkila J, Ahmad N, Tokajian S, Peters G, Schaumburg F, Olsson-Liljequist B, Givskov M, Driebe EE, Vigh HE, Shittu A, Ramdani-Bougessa N, Rasigade JP, Price LB, Vandenesch F, Larsen AR, Laurent F
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

The dynamic changes of dominant clones of Staphylococcus aureus causing bloodstream infections in the European region: Results of a second structured survey (2014)

Eurosurveillance
H Grundmann, L M Schouls2 , D M Aanensen, G N Pluister, A Tami, M Chlebowicz, C Glasner, A J Sabat, K Weist, O Heuer, A W Friedrich; on behalf of the ESCMID Study Group on Molecular Epidemiological Markers and the European Staphylococcal Reference Laboratory Working Group
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))