Jaana
Vuopio
Senior Advisor, Institute of Biomedicine
Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology
Links
Areas of expertise
• Bacterial infections and asymptomatic carriage caused by beta-hemolytic streptococci
genomic evolution of the bacterium
host susceptibility and risk factors to these infections.
• Molecular epidemiology
• Molecular epidemiology
surveillance and prevention of spread of antimicrobial resistant bacteria in humans
• Diagnostics and genomic characterization of bacterial pathogens
• Diagnostics and genomic characterization of bacterial pathogens
Research
Bacterial infections cause a significant disease burden in humans. We know that the disease spectrum can vary from asymptomatic carriage to life threatening infections.
Our aim is to gain understanding on reasons why certain individuals develop a disease and the others do not, why pathogens spread and cause epidemics and what could be the means to prevent this from happening. My long standing research interest has also resided in antimicrobial resistance, especially in molecular epidemiology and spread of MRSA, VRE and ESBL-producing Enterobacteriaceae both in health care setting and community.
Our current research areas cover:
- Invasive Group A streptococcal disease
- Molecular epidemiology and disease burden of Group A streptococcal infections
- Molecular epidemiology and spread of MRSA
- Surveillance of AMR
Research group members:
- Kirsi Gröndahl-Yli-Hannuksela, Ph.D., Adjunct professor, University teacher
- Johanna Vilhonen, M.D., Ph.D., specialist in IDs
- Tiina Hirvioja, M.D., Ph.D. fellow, specialist in IDs
- Jaakko Silvola, M.D., Ph.D. fellow
- Ville Kaila, M.D., Ph.D. fellow, specialist in IDs (based at Tampere University Hospital, Tampere)
- Erastus Haindongo, M.Sc., Ph.D. fellow (based at University of Namibia, Windhoek)
- Laura Lindholm, M.Sc., Ph.D. fellow (based at Finnish Institute of Health and Welfare)
Publications
Effect of polyinosinic-polycytidylic acid (pl:C) on experimental mouse salmonellosis (1990)
Microbial Pathogenesis
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
A strong antibody response to the periplasmic C-terminal domain of the OmpA protein of Escherichia coli is produced by immunization with purified OmpA or with whole E coli or Salmonella typhimurium bacteria (1990)
Infection and Immunity
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Lipopolysaccharide-induced non-specific resistance to systemic Escherichia coli infection in mice (1988)
Journal of Medical Microbiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Killing of Escherichia coli in the peritoneal cavity of convalescent mice; role of specific and non-specific immune mechanisms (1988)
Journal of Medical Microbiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Experimental Escherichia coli peritonitis in immunosuppressed mice: the role of specific and non-specific immunity (1988)
Journal of Medical Microbiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Protective capacity of antibodies to outer-membrane components of Escherichia coli in a systemic mouse peritonitis model (1988)
Journal of Medical Microbiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Fimbrial phase variation and systemic E coli infection studied in the mouse peritonitis model (1986)
Microbial Pathogenesis
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))