Jaana
Vuopio
Senior Advisor, Institute of Biomedicine
Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology
Links
Areas of expertise
• Bacterial infections and asymptomatic carriage caused by beta-hemolytic streptococci
genomic evolution of the bacterium
host susceptibility and risk factors to these infections.
• Molecular epidemiology
• Molecular epidemiology
surveillance and prevention of spread of antimicrobial resistant bacteria in humans
• Diagnostics and genomic characterization of bacterial pathogens
• Diagnostics and genomic characterization of bacterial pathogens
Research
Bacterial infections cause a significant disease burden in humans. We know that the disease spectrum can vary from asymptomatic carriage to life threatening infections.
Our aim is to gain understanding on reasons why certain individuals develop a disease and the others do not, why pathogens spread and cause epidemics and what could be the means to prevent this from happening. My long standing research interest has also resided in antimicrobial resistance, especially in molecular epidemiology and spread of MRSA, VRE and ESBL-producing Enterobacteriaceae both in health care setting and community.
Our current research areas cover:
- Invasive Group A streptococcal disease
- Molecular epidemiology and disease burden of Group A streptococcal infections
- Molecular epidemiology and spread of MRSA
- Surveillance of AMR
Research group members:
- Kirsi Gröndahl-Yli-Hannuksela, Ph.D., Adjunct professor, University teacher
- Johanna Vilhonen, M.D., Ph.D., specialist in IDs
- Tiina Hirvioja, M.D., Ph.D. fellow, specialist in IDs
- Jaakko Silvola, M.D., Ph.D. fellow
- Ville Kaila, M.D., Ph.D. fellow, specialist in IDs (based at Tampere University Hospital, Tampere)
- Erastus Haindongo, M.Sc., Ph.D. fellow (based at University of Namibia, Windhoek)
- Laura Lindholm, M.Sc., Ph.D. fellow (based at Finnish Institute of Health and Welfare)
Publications
Human immune response to streptococcal inhibitor of complement, a serotype M1 group A Streptococcus extracellular protein involved in epidemics (2000)
Journal of Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Finland (2000)
European Journal of Clinical Microbiology and Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Current approaches to the laboratory diagnosis of diphtheria (2000)
Journal of Infectious Diseases
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))
Molecular epidemiology of diphtheria (2000)
Journal of Infectious Diseases
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))
vanA and vanB incorporate into an endemic ampicillin-resistant vancomycin-sensitive Enterococcus faecium strain: effect on interpretation of clonality (1999)
Journal of Clinical Microbiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Rapid selection of complement-inhibiting protein variants in group A Streptococcus epidemic waves (1999)
Nature Medicine
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Neonatal group B streptococcal disease in Finland: a ten-year nationwide study (1999)
Pediatric Infectious Disease Journal
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Bacterial adherence to self-reinforced polyglycolic acid and self-reinforced polylactic acid 96 urological spiral stents in vitro (1998)
Biomaterials
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Lactobacilli and streptococci induce interleukin-12 (IL-12), IL-18, and gamma interferon production in human peripheral blood mononuclear cells (1998)
Infection and Immunity
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Clonal spread of group A streptococcus with the new type of erythromycin resistance Finnish Study Group for Antimicrobial Resistance (1998)
Journal of Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))