Jaana
Vuopio
Senior Advisor, Institute of Biomedicine
Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology
Links
Areas of expertise
• Bacterial infections and asymptomatic carriage caused by beta-hemolytic streptococci
genomic evolution of the bacterium
host susceptibility and risk factors to these infections.
• Molecular epidemiology
• Molecular epidemiology
surveillance and prevention of spread of antimicrobial resistant bacteria in humans
• Diagnostics and genomic characterization of bacterial pathogens
• Diagnostics and genomic characterization of bacterial pathogens
Research
Bacterial infections cause a significant disease burden in humans. We know that the disease spectrum can vary from asymptomatic carriage to life threatening infections.
Our aim is to gain understanding on reasons why certain individuals develop a disease and the others do not, why pathogens spread and cause epidemics and what could be the means to prevent this from happening. My long standing research interest has also resided in antimicrobial resistance, especially in molecular epidemiology and spread of MRSA, VRE and ESBL-producing Enterobacteriaceae both in health care setting and community.
Our current research areas cover:
- Invasive Group A streptococcal disease
- Molecular epidemiology and disease burden of Group A streptococcal infections
- Molecular epidemiology and spread of MRSA
- Surveillance of AMR
Research group members:
- Kirsi Gröndahl-Yli-Hannuksela, Ph.D., Adjunct professor, University teacher
- Johanna Vilhonen, M.D., Ph.D., specialist in IDs
- Tiina Hirvioja, M.D., Ph.D. fellow, specialist in IDs
- Jaakko Silvola, M.D., Ph.D. fellow
- Ville Kaila, M.D., Ph.D. fellow, specialist in IDs (based at Tampere University Hospital, Tampere)
- Erastus Haindongo, M.Sc., Ph.D. fellow (based at University of Namibia, Windhoek)
- Laura Lindholm, M.Sc., Ph.D. fellow (based at Finnish Institute of Health and Welfare)
Publications
Low expression of the CCL5 gene and low serum concentrations of CCL5 in severe invasive group a streptococcal disease (2024)
Infection
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Invasive beta-haemolytic streptococcal infections, Finland, 2006 to 2020: increase in Lancefield group C/G infections (2023)
Eurosurveillance
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Antimicrobial resistance prevalence of Escherichia coli and Staphylococcus aureus amongst bacteremic patients in Africa: a systematic review (2023)
Journal of Global Antimicrobial Resistance
(A2 Vertaisarvioitu katsausartikkeli tieteellisessä lehdessä)
Epidemiology and emm types among group A streptococcal pharyngitis in Finland: a prospective laboratory-based study (2023)
European Journal of Clinical Microbiology and Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Presence of Streptococcus pyogenes in the throat in invasive Group A Streptococcal disease: a prospective two-year study in two health districts, Finland (2023)
Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Antimicrobial resistance among bacteria isolated from urinary tract infections in females in Namibia, 2016-2017 (2022)
Antimicrobial resistance & infection control
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Detection of group A streptococcus in children with confirmed viral pharyngitis and antiviral host response (2022)
European Journal of Pediatrics
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Low rate of asymptomatic carriage and salivary immunoglobulin A response to Group A Streptococci in the healthy adult population in Finland (2022)
Medical Microbiology and Immunology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Whole genome sequencing reveals new links between spa t172/CC59 methicillin-resistant Staphylococcus aureus cases in low-endemicity region of Southwest Finland, 2007‒2016 (2022)
Scientific Reports
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Acute kidney injury in group A streptococcal bacteraemia: incidence, outcome and predictive value of C-reactive protein (2022)
Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))