Jaana
Vuopio
Senior Advisor, Institute of Biomedicine
Special Advisor, M.D. , Ph.D., Specialist in Clinical Microbiology
Links
Areas of expertise
• Bacterial infections and asymptomatic carriage caused by beta-hemolytic streptococci
genomic evolution of the bacterium
host susceptibility and risk factors to these infections.
• Molecular epidemiology
• Molecular epidemiology
surveillance and prevention of spread of antimicrobial resistant bacteria in humans
• Diagnostics and genomic characterization of bacterial pathogens
• Diagnostics and genomic characterization of bacterial pathogens
Research
Bacterial infections cause a significant disease burden in humans. We know that the disease spectrum can vary from asymptomatic carriage to life threatening infections.
Our aim is to gain understanding on reasons why certain individuals develop a disease and the others do not, why pathogens spread and cause epidemics and what could be the means to prevent this from happening. My long standing research interest has also resided in antimicrobial resistance, especially in molecular epidemiology and spread of MRSA, VRE and ESBL-producing Enterobacteriaceae both in health care setting and community.
Our current research areas cover:
- Invasive Group A streptococcal disease
- Molecular epidemiology and disease burden of Group A streptococcal infections
- Molecular epidemiology and spread of MRSA
- Surveillance of AMR
Research group members:
- Kirsi Gröndahl-Yli-Hannuksela, Ph.D., Adjunct professor, University teacher
- Johanna Vilhonen, M.D., Ph.D., specialist in IDs
- Tiina Hirvioja, M.D., Ph.D. fellow, specialist in IDs
- Jaakko Silvola, M.D., Ph.D. fellow
- Ville Kaila, M.D., Ph.D. fellow, specialist in IDs (based at Tampere University Hospital, Tampere)
- Erastus Haindongo, M.Sc., Ph.D. fellow (based at University of Namibia, Windhoek)
- Laura Lindholm, M.Sc., Ph.D. fellow (based at Finnish Institute of Health and Welfare)
Publications
Old enemies in new disguises: emergence of Enterococcus faecium as a significant clinical problem at an adult haematology ward (2017)
Infectious Diseases
(Kirjoitus tai data-artikkeli tieteellisessä aikakauslehdessä (B1))
A-ryhmän streptokokki voi aiheuttaa epidemian (2017)
Lääkärilehti
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))
Whole-Genome Sequencing for Routine Pathogen Surveillance in Public Health: a Population Snapshot of Invasive Staphylococcus aureus in Europe (2016)
mBio
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
MRSA:n epidemiologia jatkuvassa muutoksessa (2016)
Lääkärilehti
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
The psoriasis risk allele HLA-Cw0602 shows increased susceptibility to chronic/recurrent tonsillitis and points to shared T cell epitopes in these diseases (2016)
Scandinavian Journal of Immunology
(O2 Muu julkaisu )
Invasive Group A Streptococcal Infections in Children: A Nationwide Survey in Finland (2016)
Pediatric Infectious Disease Journal
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Genomic Characteristics Behind the Spread of Bacteremic Group A Streptococcus Type emm89 in Finland, 2004-2014 (2016)
Journal of Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Transcriptome Remodeling Contributes to Epidemic Disease Caused by the Human Pathogen Streptococcus pyogenes (2016)
mBio
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
A molecular trigger for intercontinental epidemics of group A Streptococcus (2015)
Journal of Clinical Investigation
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
MRSA:n torjunta erilaisia keinoja yhdistämällä on tehokasta (2015)
Duodecim
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))