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Juhani
Knuuti
Director, Turku PET Centre
InFLAMES Flagship
MD, professor, Turku PET Centre
Cardiovascular diseases, imaging
Biography
Juhani Knuuti’s research has focused on the physiology and pathophysiology, diagnosis and new therapies of coronary artery disease, heart failure and metabolic diseases. The research is also focused on developing and utilizing novel noninvasive imaging methods (PET, SPECT, echocardiography, MRI and CT) that will help to determine the risk and severity of CHD and heart failure and provide guidance for therapy decisions. The recent focus in cardiac research has been on vulnerable plaques, cardiac remodelling and multimodality and hybrid imaging. In metabolic and diabetes research, the focus has been in the interactions between different organs and heart in the pathogenesis and development of the cardiac diseases.
Publications
Performance of the American Heart Association/American College of Cardiology Guideline-Recommended Pretest Probability Model for the Diagnosis of Obstructive Coronary Artery Disease (2022)
Journal of the American Heart Association
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Atherosclerotic plaque characteristics on quantitative coronary computed tomography angiography associated with ischemia on positron emission tomography in diabetic patients (2022)
International Journal of Cardiovascular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
FFP2-maski kaikille? (2022)
Turun Sanomat
(Yleistajuinen artikkeli tai blogikirjoitus (E1))
Novel Classification of ischemia from myocardial polar maps in 15O–H2O cardiac perfusion imaging using a convolutional neural network (2022)
Scientific Reports
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Suomalaiset luottavat tieteeseen, mutta eivät kaikki (2022)
(Yleistajuinen artikkeli tai blogikirjoitus (E1))AAV2-VEGF-B gene therapy failed to induce angiogenesis in ischemic porcine myocardium due to inflammatory responses (2022)
Gene Therapy
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Association of MMP9 with adverse features of plaque progression and residual inflammatory risk in patients with chronic coronary syndrome (CCS) (2022)
Vascular Pharmacology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Selecting the right cohorts and endpoints for the validation of pre-test probability models for obstructive coronary artery disease (2021)
European Heart Journal
(Kirjoitus tai data-artikkeli tieteellisessä aikakauslehdessä (B1))
International Impact of COVID-19 on the Diagnosis of Heart Disease (2021)
Journal of the American College of Cardiology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Computed tomography coronary angiography for patients with heart failure (CTA-HF): a randomized controlled trial (IMAGE-HF 1C). (2021)
EHJ Cardiovascular Imaging / European Heart Journal - Cardiovascular Imaging
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))