Researchers from Turku Bioscience Centre and InFLAMES Flagship at the University of Turku in Finland, have identified a gene expression signature that can predict the progression of type 1 diabetes.
Researchers from the University of Turku discovered that women who developed prediabetes after pregnancy had aberrations already in their early pregnancy blood serum metabolomic profile. More specifically, they had higher concentrations of small HDL particles in early pregnancy.
Professor and Chief Physician, InFLAMES group leader Pirjo Nuutila is receiving the 2022 Novo Nordisk Foundation Lecture prize for her contribution to research on metabolic diseases such as overweight and diabetes.
Children who develop type 1 diabetes show epigenetic changes in the cells of their immune system already before the antibodies of the disease are detected in their blood. The findings of two new studies offer new opportunities to identify the children with the genetic risk for developing diabetes very early on.
Consuming the combination of fish oil and probiotic food supplements modulate the composition of gut microbiota in overweight and obese pregnant women, reveals a new study conducted at the University of Turku, Finland. The same study shows that gut microbiota composition and function is not related to gestational diabetes.
World leading diabetes research foundation JDRF from the United States has granted the University of Turku three-year funding for its PAMP project (Pathogen Associated Molecular Patterns) with the total sum of over €520,000.
Researchers from the Turku Bioscience Centre have found changes in molecules in the blood that might be new markers of type 1 diabetes. The new findings may help understand the early pathogenesis of the disease.
Enteroviral infections are common viral infections with usually rather few symptoms, and they are also believed to be linked to the onset of type 1 diabetes. Type 1 diabetes is a disorder in which the pancreatic insulin-producing beta-cells are destroyed, and it is more common in Finland than anywhere else in the world.
Using cutting-edge genomics methods a gene signature predicting type 1 diabetes was discovered. This signature is detectable already before the appearance of type 1 diabetes associated autoantibodies. The finding could help in identifying early on the children who are likely to develop the disease later.