Teemu Niiranen profile picture
Teemu
Niiranen
Professor, Internal Medicine
MD, PhD

Contact

Areas of expertise

Cardiovascular epidemiology
cohort studies
blood pressure
hypertension
blood pressure measurement

Biography

Teemu Niiranen, MD, PhD, is a physician-scientist and a clinical hypertension specialist with a track record of productivity in hypertension research, successful mentoring, international research grant procurement, and inter-institutional international collaborations. His research on hypertension in large population cohorts has led to >200 publications that are cited by the European, American, British, and Japanese clinical hypertension guidelines. These publications include first- or last-author articles in BMJ, Circulation, European Heart Journal, Nature Communications and JAMA Cardiology.

After finishing his PhD and clinical training, Dr. Niiranen received in-depth training in cardiovascular disease epidemiology and omics during a post-doctoral period at the Framingham Heart Study, the oldest and most prestigious cardiovascular cohort study in the world. After his post-doctoral period, he was selected as one of the new Group Leaders of the University of Turku Collegium of Science and Medicine and in 2020, the professor of internal medicine at the university. He is also employed as a Medical Specialist by the National Institute for Health and Welfare and chairs the work of the Cardiometabolic Clinical Expert Group of the FinnGen study, a project that has genotyped up to 500 000 unique Finnish blood samples and merged this genetic data with nationwide healthcare registers.

Dr. Niiranen has received young investigator awards from the American and Finnish Societies of Hypertension, and the American Heart Association. He is the chair of the Finnish Hypertension Society and is currently mentoring, or has mentored 12 PhD students. He is an editorial board member of Hypertension, the leading journal in hypertension research.

Teaching

Semester leadership: Fall Semester, Clinical research path for fourth year medical students.

Course leadership: PGS1728: Getting Started with Medical Research (Year 4); PGS1741: Clinical Research Literature Exam (Year 4)

Course teaching: MEDI0117: General Propedeutics (Year 4)

Pedagogic training: Medical Pedagogy course (10 credits)

Research

In addition to general cardiovascular epidemiology, Dr. Niiranen's research has focused on the epidemiology of hypertension in large scale population cohorts. His studies particularly focused on home monitoring of blood pressure and more recently he has moved into examining the relation between hypertension and omics (genome, metagenome and metabolome).

Publications

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Publisher Correction: Stroke genetics informs drug discovery and risk prediction across ancestries (vol 611, pg 115, 2022) (2022)

Nature
Mishra A, Malik R, Hachiya T, Jurgenson T, Namba S, Posner DC, Kamanu FK, Koido M, Le Grand Q, Shi MY, He YY, Georgakis MK, Caro I, Krebs K, Liaw YC, Vaura FC, Lin K, Winsvold BS, Srinivasasainagendra V, Parodi L, Bae HJ, Chauhan G, Chong MCR, Tomppo L, Akinyemi R, Roshchupkin GV, Habib N, Jee YH, Thomassen JQ, Abedi V, Carcel-Marquez J, Nygaard M, Leonard HL, Yang CJ, Yonova-Doing E, Knol MJ, Lewis AJ, Judy RL, Ago T, Amouyel P, Armstrong ND, Bakker MK, Bartz TM, Bennett DA, Bis JC, Bordes C, Borte S, Cain A, Ridker PM, Cho K, Chen ZM, Cruchaga C, Cole JW, de Jager PL, de Cid R, Endres M, Ferreira LE, Geerlings MI, Gasca NC, Gudnason V, Hata J, He J, Heath AK, Ho YL, Havulinna AS, Hopewell JC, Hyacinth HI, Inouye M, Jacob MA, Jeon CE, Jern C, Kamouchi M, Keene KL, Kitazono T, Kittner SJ, Konuma T, Kumar A, Lacaze P, Launer LJ, Lee KJ, Lepik K, Li J, Li LM, Manichaikul A, Markus HS, Marston NA, Meitinger T, Mitchell BD, Montellano FA, Morisaki T, Mosley TH, Nalls MA, Nordestgaard BG, O'Donnell MJ, Okada Y, Onland-Moret NC, Ovbiagele B, Peters A, Psaty BM, Rich SS, Rosand J, Sabatine MS, Sacco RL, Saleheen D, Sandset EC, Salomaa V, Sargurupremraj M, Sasaki M, Satizabal CL, Schmidt CO, Shimizu A, Smith NL, Sloane KL, Sutoh Y, Sun YV, Tanno K, Tiedt S, Tatlisumak T, Torres-Aguila NP, Tiwari HK, Tregouet DA, Trompet S, Tuladhar AM, Tybjaerg-Hansen A, van Vugt M, Vibo R, Verma SS, Wiggins KL, Wennberg P, Woo D, Wilson PWF, Xu HC, Yang Q, Yoon K, Bis JC, Bis JC, Lee JM, Cheng YC, Meschia JF, Chen WM, Sale MM, Zonderman AB, Evans MK, Wilson JG, Correa A, Traylor M, Lewis CM, Carty CL, Reiner A, Haessler J, Langefeld CD, Gottesman RF, Yaffe K, Liu YM, Kooperberg C, Lange LA, Furie KL, Arnett DK, Benavente OR, Grewal RP, Peddareddygari LR, Kooperberg C, Kooperberg C, Hveem K, Lindstrom S, Wang L, Smith EN, Gordon W, Vlieg AV, de Andrade M, Brody JA, Pattee JW, Haessler J, Brumpton BM, Suchon P, Chen MH, Frazer KA, Turman C, Germain M, MacDonald J, Braekkan SK, Armasu SM, Pankratz N, Jackson RD, Nielsen JB, Giulianini F, Puurunen MK, Ibrahim M, Heckbert SR, Bammler TK, McCauley BM, Taylor KD, Pankow JS, Reiner AP, Gabrielsen ME, Deleuze JF, O'Donnell CJ, Kim J, McKnight B, Kraft P, Hansen JB, Rosendaal FR, Heit JA, Tang WH, Morange PE, Johnson AD, Kabrhel C, van Dijk EJ, van Dijk EJ, Koudstaal PJ, Luijckx GJ, Nederkoorn PJ, van Oostenbrugge RJ, Visser MC, Wermer MJH, Kappelle LJ, Esko T, Esko T, Metspalu A, Magi R, Nelis M, Irvin MR, Irvin MR, de Leeuw FE, Levi CR, Maguire J, Jimenez-Conde J, Sharma P, Sudlow CLM, Rannikmae K, Schmidt R, Slowik A, Pera J, Thijs VNS, Lindgren AG, Ilinca A, Melander O, Engstrom G, Rexrode KM, Rothwell PM, Stanne TM, Johnson JA, Danesh J, Butterworth AS, Heitsch L, Boncoraglio GB, Kubo M, Pezzini A, Rolfs A, Giese AK, Weir D, Jackson RD, Ross OA, Lemmons R, Soderholm M, Cushman M, Jood K, McDonough CW, Bell S, Linkohr B, Lee TH, Putaala J, Anderson CD, Anderson CD, Lopez OL, Jian XQ, Schminke U, Cullell N, Delgado P, Ibanez L, Krupinski J, Lioutas V, Matsuda K, Montaner J, Muino E, Roquer J, Sarnowski C, Sattar N, Sibolt G, Teumer A, Rutten-Jacobs L, Kanai M, Giese AK, Gretarsdottir S, Rost NS, Yusuf S, Almgren P, Ay H, Bevan S, Brown RD, Carrera C, Buring JE, Chen WM, Cotlarciuc I, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Gustafsson S, Hassan A, Holliday EG, Howard G, Hsu FC, Ingelsson E, Harris TB, Kissela BM, Kleindorfer DO, Langenberg C, Lemmens R, Leys D, Lin WY, Lorentzen E, Magnusson PK, McArdle PF, Pulit SL, Rice K, Sakaue S, Sapkota BR, Tanislav C, Thorleifsson G, Thorsteinsdottir U, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Amin N, Aparicio HJ, Attia J, Beiser AS, Berr C, Bustamante M, Caso V, Choi SH, Chowhan A, Dartigues JF, Delavaran H, Dorr M, Ford I, Gurpreet WS, Hamsten A, Hozawa A, Ingelsson M, Iwasaki M, Kaffashian S, Kalra L, Kjartansson O, Kloss M, Labovitz DL, Laurie CC, Li LN, Lind L, Lindgren CM, Makoto H, Minegishi N, Morris AP, Muller-Nurasyid M, Norrving B, Ogishima S, Parati EA, Pedersen NL, Perola M, Jousilahti P, Pileggi S, Rabionet R, Riba-Llena I, Ribases M, Romero JR, Rudd AG, Sarin AP, Sarju R, Satoh M, Sawada N, Sigurdsson A, Smith A, Stine OC, Stott DJ, Strauch K, Takai T, Tanaka H, Touze E, Tsugane S, Uitterlinden AG, Valdimarsson EM, van der Lee SJ, Wakai K, Williams SR, Wolfe CDA, Wong QN, Yamaji T, Sanghera DK, Stefansson K, Taylor KD, Martinez-Majander N, Sobue K, Soriano-Tarraga C, Volzke H, Akpa O, Akpa O, Sarfo FS, Akpalu A, Obiako R, Wahab K, Osaigbovo G, Owolabi L, Komolafe M, Jenkins C, Arulogun O, Ogbole G, Adeoye AM, Akinyemi J, Agunloye A, Fakunle AG, Uvere E, Olalere A, Adebajo OJ, Chen JS, Chen JS, Clarke R, Collins R, Guo Y, Wang C, Lv J, Peto R, Chen YP, Fairhurst-Hunter Z, Hill M, Pozarickij A, Schmidt D, Stevens B, Turnbull I, Yu CQ, Le Grand Q, Le Grand Q, Ferreira LE, Nagai A, Nagai A, Murakami Y, Geerlings MI, Geerlings MI, Gasca NC, Gudnason V, van Vugt M, Gottesman RF, Shiroma EJ, Sigurdsson S, Ghanbari M, Boerwinkle E, Beiser AS, Fongang B, Wang RQ, Ikram MK, Volker U, de Jager PL, de Jager PL, de Cid R, Nordestgaard BG, Sargurupremraj M, Verma SS, de Laat KF, de Laat KF, van Norden AGW, de Kort PL, Vermeer SE, Brouwers PJAM, Gons RAR, Nederkoorn PJ, den Heijer T, van Dijk GW, van Rooij FGW, Aamodt AH, Aamodt AH, Skogholt AH, Brumpton BM, Willer CJ, Heuch I, Hagen K, Fritsche LG, Pedersen LM, Gabrielsen ME, Ellekjaer H, Zhou W, Martinsen AE, Kristoffersen ES, Nielsen JB, Hveem K, Thomas LF, Kleinschnitz C, Kleinschnitz C, Frantz S, Ungethum K, Gallego-Fabrega C, Gallego-Fabrega C, Lledos M, Llucia-Carol L, Sobrino T, Campos F, Castillo J, Freijo M, Arenillas JF, Obach V, alvarez-Sabin J, Molina CA, Ribo M, Munoz-Narbona L, Lopez-Cancio E, Millan M, Diaz-Navarro R, Vives-Bauza C, Serrano-Heras G, Segura T, Delgado P, Dhar R, Delgado-Mederos R, Prats-Sanchez L, Camps-Renom P, Blay N, Sumoy L, Marti-Fabregas J, Schnohr P, Schnohr P, Jensen GB, Benn M, Afzal S, Kamstrup PR, van Setten J, van Setten J, van der Laan SW, Vonk JMJ, Kim BJ, Kim BJ, Curtze S, Curtze S, Tiainen M, Kinnunen J, Menon V, Menon V, Sung YJ, Yang CR, Saillour-Glenisson F, Gravel S, Onland-Moret NC, Onland-Moret NC, Heath AK, Millwood IY, Gieger C, Ninomiya T, Grabe HJ, Jukema JW, Rissanen IL, Strbian D, Kim YJ, Chen PH, Mayerhofer E, Howson JMM, Irvin MR, Adams H, Wassertheil-Smoller S, Christensen K, Ikram MA, Rundek T, Worrall BB, Lathrop GM, Riaz M, Simonsick EM, Korv J, Franca PHC, Zand R, Prasad K, Frikke-Schmidt R, de Leeuw FE, Liman T, Haeusler KG, Ruigrok YM, Heuschmann PU, Longstreth WT, Jung KJ, Bastarache L, Pare G, Damrauer SM, Chasman DI, Rotter JI, Anderson CD, Zwart JA, Niiranen TJ, Fornage M, Liaw YP, Seshadri S, Fernandez-Cadenas I, Walters RG, Ruff CT, Owolabi MO, Huffman JE, Milani L, Kamatani Y, Dichgans M, Debette S
(O2 Muu julkaisu )

Sex Differences in Myocardial and Vascular Aging (2022)

Circulation Research
Ji Hongwei W, Kwan Alan C, Chen Melanie T, Ouyang David, Ebinger Joseph E, Bell Susan P, Niiranen Teemu J, Bello Natalie A, Cheng Susan
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))

Early prediction of incident liver disease using conventional risk factors and gut-microbiome-augmented gradient boosting (2022)

Cell Metabolism
Liu Yang, Méric Guillaume, Havulinna Aki S, Teo Shu Mei, Åberg Fredrik, Ruuskanen Matti, Sanders Jon, Zhu Qiyun, Tripathi Anupriya, Verspoor Karin, Cheng Susan, Jain Mohit, Jousilahti Pekka, Vázquez-Baeza Yoshiki, Loomba Rohit, Lahti Leo, Niiranen Teemu, Salomaa Veikko, Knight Rob, Inouye Michael
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

The genomics of heart failure: design and rationale of the HERMES consortium (2022)

ESC Heart Failure
Lumbers R. Thomas, Shah Sonia, Lin Honghuang, Czuba Tomasz, Henry Albert, Swerdlow Daniel I., Mälarstig Anders, Andersson Charlotte, Verweij Niek, Holmes Michael V., Ärnlöv Johan, Svensson Per, Hemingway Harry, Sallah Neneh, Almgren Peter, Aragam Krishna G., Asselin Geraldine, Backman Joshua D., Biggs Mary L.L, Bloom Heather L., Boersma Eric, Brandimarto Jeffrey, Brown Michael R., Brunner-La Rocca Hans-Peter, Carey David J., Chaffin Mark D., Chasman Daniel I., Chazara Olympe, Chen Xing, Chen Xu, Chung Jonathan H., Chutkow William, Cleland John G.F., Cook James P., de Denus Simon, Dehghan Abbas, Delgado Graciela E., Denaxas Spiros, Doney Alexander S., Dörr Marcus, Dudley Samuel C., Engström Gunnar, Esko Tõnu, Fatemifar Ghazaleh, Felix Stephan B., Finan Chris, Ford Ian, Fougerousse Francoise, Fouodjio René, Ghanbari Mohsen, Ghasemi Sahar, Giedraitis Vilmantas, Giulianini Franco, Gottdiener John S., Gross Stefan, Guðbjartsson Daníel F., Gui Hongsheng, Gutmann Rebecca, Haggerty Christopher M., van der Harst Pim, Hedman Åsa K., Helgadottir Anna, Hillege Hans, Hyde Craig L., Jacob Jaison, Jukema J. Wouter, Kamanu Frederick, Kardys Isabella, Kavousi Maryam, Khaw Kay-Tee, Kleber Marcus E., Køber Lars, Koekemoer Andrea, Kraus Bill, Kuchenbaecker Karoline, Langenberg Claudia, Lind Lars, Lindgren Cecilia M., London Barry, Lotta Luca A., Lovering Ruth C., Luan Jian’an, Magnusson Patrik, Mahajan Anubha, Mann Douglas, Margulies Kenneth B., Marston Nicholas A., März Winfried, McMurray John J.V., Melander Olle, Melloni Giorgio, Mordi Ify R., Morley Michael P., Morris Andrew D., Morris Andrew P., Morrison Alanna C., Nagle Michael W., Nelson Christopher P., Newton-Cheh Christopher , Niessner Alexander, Niiranen Teemu, Nowak Christoph, O'Donoghue Michelle L., Owens Anjali T., Palmer Colin N.A., Paré Guillaume, Perola Markus, Perreault Louis-Philippe Lemieux, Portilla-Fernandez Eliana, Psaty Bruce M., Rice Kenneth M., Ridker Paul M., Romaine Simon P.R., Roselli Carolina, Rotter Jerome I., Ruff Christian T., Sabatine Marc S., Salo Perttu, Salomaa Veikko, van Setten Jessica, Shalaby Alaa A., Smelser Diane T., Smith Nicholas L., Stefansson Kari, Stender Steen, Stott David J., Sveinbjörnsson Garðar, Tammesoo Mari-Liis, Tardif Jean-Claude, Taylor Kent D., Teder-Laving Maris, Teumer Alexander, Thorgeirsson Guðmundur, Thorsteinsdottir Unnur, Torp-Pedersen Christian, Trompet Stella, Tuckwell Danny, Tyl Benoit, Uitterlinden Andre G., Vaura F, Veluchamy Abirami, Visscher Peter M., Völker Uwe, Voors Adriaan A., Wang Xiaosong, Wareham Nicholas J., Weeke Peter E., Weiss Raul, White Harvey D., Wiggins Kerri L., Xing Heming, Yang Jian, Yang Yifan, Yerges-Armstrong Laura M., Yu Bing, Zannad Faiez, Zhao Faye, Wilk Jemma B., Holm Hilma, Sattar Naveed, Lubitz Steven A., Lanfear David E., Shah Svati, Dunn Michael E., Wells Quinn S., Asselbergs Folkert W., Hingorani Aroon D., Dubé Marie-Pierre, Samani Nilesh J., Lang Chim C., Cappola Thomas P., Ellinor Patrick T., Vasan Ramachandran S., Smith J. Gustav
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort (2022)

Nature Genetics
Qin Youwen, Havulinna Aki S., Liu Yang, Jousilahti Pekka, Ritchie Scott C., Tokolyi Alex, Sanders Jon G., Valsta Liisa, Brozynska Marta, Zhu Qiyun, Tripathi Anupriya, Vázquez-Baeza Yoshiki, Loomba Rohit, Cheng Susan, Jain Mohit, Niiranen Teemu, Lahti Leo, Knight Rob, Salomaa Veikko, Inouye Michael, Méric Guillaume
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes: a prospective study in three independent cohorts (2022)

BMJ open diabetes research and care
Tuomisto Karolina, Palmu Joonatan, Long Tao, Watrous Jeramie D, Mercader Kysha, Lagerborg Kim A, Andres Allen, Salmi Marko, Jalkanen Sirpa, Vasan Ramachandran S, Inouye Michael, Havulinna Aki S, Tuomilehto Jaakko, Jousilahti Pekka, Niiranen Teemu J, Cheng Susan, Jain Mohit, Salomaa Veikko
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))