Teemu Niiranen profile picture
Teemu
Niiranen
Professor, Internal Medicine
MD, PhD

Contact

Areas of expertise

Cardiovascular epidemiology
cohort studies
blood pressure
hypertension
blood pressure measurement

Biography

Teemu Niiranen, MD, PhD, is a physician-scientist and a clinical hypertension specialist with a track record of productivity in hypertension research, successful mentoring, international research grant procurement, and inter-institutional international collaborations. His research on hypertension in large population cohorts has led to >200 publications that are cited by the European, American, British, and Japanese clinical hypertension guidelines. These publications include first- or last-author articles in BMJ, Circulation, European Heart Journal, Nature Communications and JAMA Cardiology.

After finishing his PhD and clinical training, Dr. Niiranen received in-depth training in cardiovascular disease epidemiology and omics during a post-doctoral period at the Framingham Heart Study, the oldest and most prestigious cardiovascular cohort study in the world. After his post-doctoral period, he was selected as one of the new Group Leaders of the University of Turku Collegium of Science and Medicine and in 2020, the professor of internal medicine at the university. He is also employed as a Medical Specialist by the National Institute for Health and Welfare and chairs the work of the Cardiometabolic Clinical Expert Group of the FinnGen study, a project that has genotyped up to 500 000 unique Finnish blood samples and merged this genetic data with nationwide healthcare registers.

Dr. Niiranen has received young investigator awards from the American and Finnish Societies of Hypertension, and the American Heart Association. He is the chair of the Finnish Hypertension Society and is currently mentoring, or has mentored 12 PhD students. He is an editorial board member of Hypertension, the leading journal in hypertension research.

Teaching

Semester leadership: Fall Semester, Clinical research path for fourth year medical students.

Course leadership: PGS1728: Getting Started with Medical Research (Year 4); PGS1741: Clinical Research Literature Exam (Year 4)

Course teaching: MEDI0117: General Propedeutics (Year 4)

Pedagogic training: Medical Pedagogy course (10 credits)

Research

In addition to general cardiovascular epidemiology, Dr. Niiranen's research has focused on the epidemiology of hypertension in large scale population cohorts. His studies particularly focused on home monitoring of blood pressure and more recently he has moved into examining the relation between hypertension and omics (genome, metagenome and metabolome).

Publications

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The genomics of heart failure: design and rationale of the HERMES consortium (2022)

ESC Heart Failure
Lumbers R. Thomas, Shah Sonia, Lin Honghuang, Czuba Tomasz, Henry Albert, Swerdlow Daniel I., Mälarstig Anders, Andersson Charlotte, Verweij Niek, Holmes Michael V., Ärnlöv Johan, Svensson Per, Hemingway Harry, Sallah Neneh, Almgren Peter, Aragam Krishna G., Asselin Geraldine, Backman Joshua D., Biggs Mary L.L, Bloom Heather L., Boersma Eric, Brandimarto Jeffrey, Brown Michael R., Brunner-La Rocca Hans-Peter, Carey David J., Chaffin Mark D., Chasman Daniel I., Chazara Olympe, Chen Xing, Chen Xu, Chung Jonathan H., Chutkow William, Cleland John G.F., Cook James P., de Denus Simon, Dehghan Abbas, Delgado Graciela E., Denaxas Spiros, Doney Alexander S., Dörr Marcus, Dudley Samuel C., Engström Gunnar, Esko Tõnu, Fatemifar Ghazaleh, Felix Stephan B., Finan Chris, Ford Ian, Fougerousse Francoise, Fouodjio René, Ghanbari Mohsen, Ghasemi Sahar, Giedraitis Vilmantas, Giulianini Franco, Gottdiener John S., Gross Stefan, Guðbjartsson Daníel F., Gui Hongsheng, Gutmann Rebecca, Haggerty Christopher M., van der Harst Pim, Hedman Åsa K., Helgadottir Anna, Hillege Hans, Hyde Craig L., Jacob Jaison, Jukema J. Wouter, Kamanu Frederick, Kardys Isabella, Kavousi Maryam, Khaw Kay-Tee, Kleber Marcus E., Køber Lars, Koekemoer Andrea, Kraus Bill, Kuchenbaecker Karoline, Langenberg Claudia, Lind Lars, Lindgren Cecilia M., London Barry, Lotta Luca A., Lovering Ruth C., Luan Jian’an, Magnusson Patrik, Mahajan Anubha, Mann Douglas, Margulies Kenneth B., Marston Nicholas A., März Winfried, McMurray John J.V., Melander Olle, Melloni Giorgio, Mordi Ify R., Morley Michael P., Morris Andrew D., Morris Andrew P., Morrison Alanna C., Nagle Michael W., Nelson Christopher P., Newton-Cheh Christopher , Niessner Alexander, Niiranen Teemu, Nowak Christoph, O'Donoghue Michelle L., Owens Anjali T., Palmer Colin N.A., Paré Guillaume, Perola Markus, Perreault Louis-Philippe Lemieux, Portilla-Fernandez Eliana, Psaty Bruce M., Rice Kenneth M., Ridker Paul M., Romaine Simon P.R., Roselli Carolina, Rotter Jerome I., Ruff Christian T., Sabatine Marc S., Salo Perttu, Salomaa Veikko, van Setten Jessica, Shalaby Alaa A., Smelser Diane T., Smith Nicholas L., Stefansson Kari, Stender Steen, Stott David J., Sveinbjörnsson Garðar, Tammesoo Mari-Liis, Tardif Jean-Claude, Taylor Kent D., Teder-Laving Maris, Teumer Alexander, Thorgeirsson Guðmundur, Thorsteinsdottir Unnur, Torp-Pedersen Christian, Trompet Stella, Tuckwell Danny, Tyl Benoit, Uitterlinden Andre G., Vaura F, Veluchamy Abirami, Visscher Peter M., Völker Uwe, Voors Adriaan A., Wang Xiaosong, Wareham Nicholas J., Weeke Peter E., Weiss Raul, White Harvey D., Wiggins Kerri L., Xing Heming, Yang Jian, Yang Yifan, Yerges-Armstrong Laura M., Yu Bing, Zannad Faiez, Zhao Faye, Wilk Jemma B., Holm Hilma, Sattar Naveed, Lubitz Steven A., Lanfear David E., Shah Svati, Dunn Michael E., Wells Quinn S., Asselbergs Folkert W., Hingorani Aroon D., Dubé Marie-Pierre, Samani Nilesh J., Lang Chim C., Cappola Thomas P., Ellinor Patrick T., Vasan Ramachandran S., Smith J. Gustav
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort (2022)

Nature Genetics
Qin Youwen, Havulinna Aki S., Liu Yang, Jousilahti Pekka, Ritchie Scott C., Tokolyi Alex, Sanders Jon G., Valsta Liisa, Brozynska Marta, Zhu Qiyun, Tripathi Anupriya, Vázquez-Baeza Yoshiki, Loomba Rohit, Cheng Susan, Jain Mohit, Niiranen Teemu, Lahti Leo, Knight Rob, Salomaa Veikko, Inouye Michael, Méric Guillaume
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

A plasma metabolite score of three eicosanoids predicts incident type 2 diabetes: a prospective study in three independent cohorts (2022)

BMJ open diabetes research and care
Tuomisto Karolina, Palmu Joonatan, Long Tao, Watrous Jeramie D, Mercader Kysha, Lagerborg Kim A, Andres Allen, Salmi Marko, Jalkanen Sirpa, Vasan Ramachandran S, Inouye Michael, Havulinna Aki S, Tuomilehto Jaakko, Jousilahti Pekka, Niiranen Teemu J, Cheng Susan, Jain Mohit, Salomaa Veikko
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Stroke genetics informs drug discovery and risk prediction across ancestries (2022)

Nature
Mishra Aniket, Malik Rainer, Hachiya Tsuyoshi, Jürgenson Tuuli, Namba Shinichi, Posner Daniel C., Kamanu Frederick K., Koido Masaru, Le Grand Quentin, Shi Mingyang, He Yunye, Georgakis Marios K., Caro Ilana, Krebs Kristi, Liaw Yi-Ching, Vaura Felix C., Lin Kuang, Winsvold Bendik Slagsvold, Srinivasasainagendra Vinodh, Parodi Livia, Bae Hee-Joon, Chauhan Ganesh, Chong Michael R., Tomppo Liisa, Akinyemi Rufus, Roshchupkin Gennady V., Habib Naomi, Jee Yon Ho, Thomassen Jesper Qvist, Abedi Vida, Cárcel-Márquez Jara, Nygaard Marianne, Leonard Hampton L., Yang Chaojie, Yonova-Doing Ekaterina, Knol Maria J., Lewis Adam J., Judy Renae L., Ago Tetsuro, Amouyel Philippe, Armstrong Nicole D., Bakker Mark K., Bartz Traci M., Bennett David A., Bis Joshua C., Bordes Constance, Børte Sigrid, Cain Anael, Ridker Paul M., Cho Kelly, Chen Zhengming, Cruchaga Carlos, Cole John W., de Jager Phil L., de Cid Rafael, Endres Matthias, Ferreira Leslie E., Geerlings Mirjam I., Gasca Natalie C., Gudnason Vilmundur, Hata Jun, He Jing, Heath Alicia K., Ho Yuk-Lam, Havulinna Aki S., Hopewell Jemma C., Hyacinth Hyacinth I., Inouye Michael, Jacob Mina A., Jeon Christina E., Jern Christina, Kamouchi Masahiro, Keene Keith L., Kitazono Takanari, Kittner Steven J., Konuma Takahiro, Kumar Amit, Lacaze Paul, Launer Lenore J., Lee Keon-Joo, Lepik Kaido, Li Jiang, Li Liming, Manichaikul Ani, Markus Hugh S., Marston Nicholas A., Meitinger Thomas, Mitchell Braxton D., Montellano Felipe A., Morisaki Takayuki, Mosley Thomas H., Nalls Mike A., Nordestgaard Børge G., O'Donnell Martin J., Okada Yukinori, Onland-Moret N. Charlotte, Ovbiagele Bruce, Peters Annette, Psaty Bruce M., Rich Stephen S., Rosand Jonathan, Sabatine Marc S., Sacco Ralph L., Saleheen Danish, Sandset Else Charlotte, Salomaa Veikko, Sargurupremraj Muralidharan, Sasaki Makoto, Satizabal Claudia L., Schmidt Carsten O., Shimizu Atsushi, Smith Nicholas L., Sloane Kelly L., Sutoh Yoichi, Sun Yan V., Tanno Kozo, Tiedt Steffen, Tatlisumak Turgut, Torres-Aguila Nuria P., Tiwari Hemant K., Trégouët David-Alexandre, Trompet Stella, Tuladhar Anil Man, Tybjærg-Hansen Anne, van Vugt Marion, Vibo Riina, Verma Stefali S., Wiggins Kerri L., Wennberg Patrik, Woo Daniel, Wilson Peter W. F., Xu Huichun , Yang Qiong, Yoon Kyungheon, Bis JC, Bis JC, Lee JM, Cheng YC, Meschia JF, Chen WM, Sale MM, Zonderman AB, Evans MK, Wilson JG, Correa A, Traylor M, Lewis CM, Carty CL, Reiner A, Haessler J, Langefeld CD, Gottesman RF, Yaffe K, Liu YM, Kooperberg C, Lange LA, Furie KL, Arnett DK, Benavente OR, Grewal RP, Peddareddygari LR, Kooperberg C, Kooperberg C, Hveem K, Lindstrom S, Wang L, Smith EN, Gordon W, Vlieg AV, de Andrade M, Brody JA, Pattee JW, Haessler J, Brumpton BM, Suchon P, Chen MH, Frazer KA, Turman C, Germain M, MacDonald J, Braekkan SK, Armasu SM, Pankratz N, Jackson RD, Nielsen JB, Giulianini F, Puurunen MK, Ibrahim M, Heckbert SR, Bammler TK, McCauley BM, Taylor KD, Pankow JS, Reiner AP, Gabrielsen ME, Deleuze JF, O'Donnell CJ, Kim J, McKnight B, Kraft P, Hansen JB, Rosendaal FR, Heit JA, Tang WH, Morange PE, Johnson AD, Kabrhel C, van Dijk EJ, van Dijk EJ, Koudstaal PJ, Luijckx GJ, Nederkoorn PJ, van Oostenbrugge RJ, Visser MC, Wermer MJH, Kappelle LJ, Esko T, Esko T, Metspalu A, Magi R, Nelis M, Irvin MR, Irvin MR, de Leeuw FE, Levi CR, Maguire J, Jimenez-Conde J, Sharma P, Sudlow CLM, Rannikmae K, Schmidt R, Slowik A, Pera J, Thijs VNS, Lindgren AG, Ilinca A, Melander O, Engstrom G, Rexrode KM, Rothwell PM, Stanne TM, Johnson JA, Danesh J, Butterworth AS, Heitsch L, Boncoraglio GB, Kubo M, Pezzini A, Rolfs A, Giese AK, Weir D, Jackson RD, Ross OA, Lemmons R, Soderholm M, Cushman M, Jood K, McDonough CW, Bell S, Linkohr B, Lee TH, Putaala J, Anderson CD, Anderson CD, Lopez OL, Jian XQ, Schminke U, Cullell N, Delgado P, Ibanez L, Krupinski J, Lioutas V, Matsuda K, Montaner J, Muino E, Roquer J, Sarnowski C, Sattar N, Sibolt G, Teumer A, Rutten-Jacobs L, Kanai M, Giese AK, Gretarsdottir S, Rost NS, Yusuf S, Almgren P, Ay H, Bevan S, Brown RD, Carrera C, Buring JE, Chen WM, Cotlarciuc I, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Gustafsson S, Hassan A, Holliday EG, Howard G, Hsu FC, Ingelsson E, Harris TB, Kissela BM, Kleindorfer DO, Langenberg C, Lemmens R, Leys D, Lin WY, Lorentzen E, Magnusson PK, McArdle PF, Pulit SL, Rice K, Sakaue S, Sapkota BR, Tanislav C, Thorleifsson G, Thorsteinsdottir U, Tzourio C, van Duijn CM, Walters M, Wareham NJ, Amin N, Aparicio HJ, Attia J, Beiser AS, Berr C, Bustamante M, Caso V, Choi SH, Chowhan A, Dartigues JF, Delavaran H, Dorr M, Ford I, Gurpreet WS, Hamsten A, Hozawa A, Ingelsson M, Iwasaki M, Kaffashian S, Kalra L, Kjartansson O, Kloss M, Labovitz DL, Laurie CC, Li LN, Lind L, Lindgren CM, Makoto H, Minegishi N, Morris AP, Muller-Nurasyid M, Norrving B, Ogishima S, Parati EA, Pedersen NL, Perola M, Jousilahti P, Pileggi S, Rabionet R, Riba-Llena I, Ribases M, Romero JR, Rudd AG, Sarin AP, Sarju R, Satoh M, Sawada N, Sigurdsson A, Smith A, Stine OC, Stott DJ, Strauch K, Takai T, Tanaka H, Touze E, Tsugane S, Uitterlinden AG, Valdimarsson EM, van der Lee SJ, Wakai K, Williams SR, Wolfe CDA, Wong QN, Yamaji T, Sanghera DK, Stefansson K, Taylor KD, Martinez-Majander N, Sobue K, Soriano-Tarraga C, Volzke H, Akpa O, Akpa O, Sarfo FS, Akpalu A, Obiako R, Wahab K, Osaigbovo G, Owolabi L, Komolafe M, Jenkins C, Arulogun O, Ogbole G, Adeoye AM, Akinyemi J, Agunloye A, Fakunle AG, Uvere E, Olalere A, Adebajo OJ, Chen JS, Chen JS, Clarke R, Collins R, Guo Y, Wang C, Lv J, Peto R, Chen YP, Fairhurst-Hunter Z, Hill M, Pozarickij A, Schmidt D, Stevens B, Turnbull I, Yu CQ, Le Grand Q, Le Grand Q, Ferreira LE, Nagai A, Nagai A, Murakami Y, Geerlings MI, Geerlings MI, Gasca NC, Gudnason V, van Vugt M, Gottesman RF, Shiroma EJ, Sigurdsson S, Ghanbari M, Boerwinkle E, Beiser AS, Fongang B, Wang RQ, Ikram MK, Volker U, de Jager PL, de Jager PL, de Cid R, Nordestgaard BG, Sargurupremraj M, Verma SS, de Laat KF, de Laat KF, van Norden AGW, de Kort PL, Vermeer SE, Brouwers PJAM, Gons RAR, Nederkoorn PJ, den Heijer T, van Dijk GW, van Rooij FGW, Aamodt AH, Aamodt AH, Skogholt AH, Brumpton BM, Willer CJ, Heuch I, Hagen K, Fritsche LG, Pedersen LM, Gabrielsen ME, Ellekjaer H, Zhou W, Martinsen AE, Kristoffersen ES, Nielsen JB, Hveem K, Thomas LF, Kleinschnitz C, Kleinschnitz C, Frantz S, Ungethum K, Gallego-Fabrega C, Gallego-Fabrega C, Lledos M, Llucia-Carol L, Sobrino T, Campos F, Castillo J, Freijo M, Arenillas JF, Obach V, Alvarez-Sabin J, Molina CA, Ribo M, Munoz-Narbona L, Lopez-Cancio E, Millan M, Diaz-Navarro R, Vives-Bauza C, Serrano-Heras G, Segura T, Delgado P, Dhar R, Delgado-Mederos R, Prats-Sanchez L, Camps-Renom P, Blay N, Sumoy L, Marti-Fabregas J, Schnohr P, Schnohr P, Jensen GB, Benn M, Afzal S, Kamstrup PR, van Setten J, van Setten J, van der Laan SW, Vonk JMJ, Kim BJ, Kim BJ, Curtze S, Curtze S, Tiainen M, Kinnunen J, Menon V, Menon V, Sung YJ, Yang CR, Saillour-Glenisson F, Gravel S, Onland-Moret NC, Onland-Moret NC, Heath AK, Millwood Iona Y., Gieger Christian, Ninomiya Toshiharu, Grabe Hans J., Jukema J. Wouter, Rissanen Ina L., Strbian Daniel, Kim Young Jin, Chen Pei-Hsin, Mayerhofer Ernst, Howson Joanna M. M., Irvin Marguerite R., Adams Hieab, Wassertheil-Smoller Sylvia, Christensen Kaare, Ikram Mohammad A., Rundek Tatjana, Worrall Bradford B., Lathrop G. Mark, Riaz Moeen, Simonsick Eleanor M., Kõrv Janika, França Paulo H. C., Zand Ramin, Prasad Kameshwar, Frikke-Schmidt Ruth, de Leeuw Frank-Erik, Liman Thomas, Haeusler Karl Georg, Ruigrok Ynte M., Heuschmann Peter Ulrich, Longstreth W. T., Jung Keum J., Bastarache Lisa, Paré Guillaume, Damrauer Scott M., Chasman Daniel I., Rotter Jerome I., Anderson Christopher D., Zwart John-Anker, Niiranen Teemu J., Fornage Myriam, Liaw Yung-Po, Seshadri Sudha, Fernández-Cadenas Israel, Walters Robin G., Ruff Christian T., Owolabi Mayowa O., Huffman Jennifer E., Milani Lili, Kamatani Yoichiro, Dichgans Martin, Debette Stephanie
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

The International Database of Central Arterial Properties for Risk Stratification: Research Objectives and Baseline Characteristics of Participants (2022)

American Journal of Hypertension
Aparicio LS, Huang QF, Melgarejo JD, Wei DM, Thijs L, Wei FF, Gilis-Malinowska N, Sheng CS, Boggia J, Niiranen TJ, Odili AN, Stolarz-Skrzypek K, Barochiner J, Ackermann D, Kawecka-Jaszcz K, Tikhonoff V, Zhang ZY, Casiglia E, Narkiewicz K, Filipovský J, Schutte AE, Yang WY, Jula AM, Woodiwiss AJ, Bochud M, Norton GR, Wang JG, Li Y, Staessen JA, International Database of Central Arterial Properties for Risk Stratification (IDCARS) Investigators
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Cuffless blood pressure measuring devices: review and statement by the European Society of Hypertension Working Group on Blood Pressure Monitoring and Cardiovascular Variability (2022)

Journal of Hypertension
Stergiou George S, Mukkamala Ramakrishna, Avolio Alberto, Kyriakoulis Konstantinos G, Mieke Stephan, Murray Alan, Parati Gianfranco, Schutte Aletta E, Sharman James E, Asmar Roland, McManus Richard J, Asayama Kei, De la Sierra Alejandro, Head Geoffrey, Kario Kazuomi, Kollias Anastasios, Myers Martin, Niiranen Teemu, Ohkubo Takayoshi, Wang Jiguang, Wuerzner Gregoire, O'Brien Eoin, Kreutz Reinhold, Palatini Paolo
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))

Phylogeny-Aware Analysis of Metagenome Community Ecology Based on Matched Reference Genomes while Bypassing Taxonomy (2022)

MSystems
Zhu Qiyun, Huang Shi, Gonzalez Antonio, McGrath Imran, McDonald Daniel, Haiminen Niina, Armstrong George, Vázquez-Baeza Yoshiki, Yu Julian, Kuczynski Justin, Sepich-Poore Gregory D., Swafford Austin D., Das Promi, Shaffer Justin P., Lejzerowicz Franck, Belda-Ferre Pedro, Havulinna Aki S., Méric Guillaume, Niiranen Teemu, Lahti Leo, Salomaa Veikko, Kim Ho-Cheol, Jain Mohit, Inouye Michael, Gilbert Jack A., Knight Rob
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))