Tapio Lönnberg profile picture
Tapio
Lönnberg
Senior Research Fellow, Turku Bioscience Centre
InFLAMES Flagship
Docent, Biotechnology
PhD
Single-cell immunogenomics research group at Turku Bioscience Centre; InFLAMES Flagship

Contact

+358 29 450 3738
Tykistökatu 6
20520
Turku

Areas of expertise

Single-cell genomics
immunology

Biography

  • Phd 2012, University of Turku, supervised by Prof. Riitta Lahesmaa and Prof. Matej Orešič
  • Postdoc 2023-2016, Teichmann lab, EMBL-EBI and Wellcome Trust Sanger Institute, UK
  • Academy of Finland postdoc 2017-2020, Turku Bioscience Centre, University of Turku
  • 2021- Group Leader at InFLAMES Flagship
  • Secretary of the Finnish Society for Immunology



Teaching

  • Modern biotechnologies and bioinformatics
  • Medical biotechnology
  • Advanced Immunology


Research

Our research aims at gaining deeper understanding of cell fate decisions in the immune system. We leverage single-cell and spatial omics to explore phenotypic heterogeneity beyond the immune cell subsets defined by the expression of cell surface markers. Our current research encompasses arthritic, autoimmune and cardiovascular diseases, aiming to identify core gene modules that are associated with disease state and can be exploited for more efficient diagnosis, patient stratification, and therapies.

Publications

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PIM kinases regulate early human Th17 cell differentiation (2023)

Cell Reports
Buchacher Tanja, Shetty Ankitha, Koskela Saara A., Smolander Johannes, Kaukonen Riina, Sousa Antonio G. G., Junttila Sini, Laiho Asta, Rundquist Olof, Lonnberg Tapio, Marson Alexander, Rasool Omid, L. Laura, Lahesmaa Riitta
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Single-cell characterization of leukemic and non-leukemic immune repertoires in CD8+ T-cell large granular lymphocytic leukemia (2022)

Nature Communications
Huuhtanen Jani, Bhattacharya Dipabarna, Lönnberg Tapio, Kankainen Matti, Kerr Cassandra, Theodoropoulos Jason, Rajala Hanna, Gurnari Carmelo, Kasanen Tiina, Braun Till, Teramo Antonella, Zambello Renato, Herling Marco, Ishida Fumihiro, Kawakami Toru, Salmi Marko, Loughran Thomas, Maciejewski Jaroslaw P., Lähdesmäki Harri, Kelkka Tiina, Mustjoki Satu
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))