Olli Tenovuo profile picture
Olli
Tenovuo
Docent, Faculty of Medicine
MD, PhD, Prof. of Neurotraumatology
Pathophysiology, diagnostics, treatment, and prognosis of traumatic brain injury

Contact

Areas of expertise

traumatic brain injury
rehabilitation
biomarkers
imaging

Biography

I have a long and profound experience in the field of traumatic brain injuries (TBIs), both clinically and scientifically. Patients with TBI of different severities have been my main clinical interest since early 1990’s, and during the years I have treated about 6 000 patients with TBI. Since 1996 I have led a multidisciplinary research group on TBIs, which has expanded steadily. Currently our group includes > 40 researchers, 21 of which are PhD students and 7 are post docs. They represent widely different disciplines, such as neurosurgery, neurology, neuroanaesthesiology, neuroradiology, neuropsychology, clinical neurophysiology, psychiatry etc. I have conducted also large international research projects and am currently in a leading position in several trials. I have also experience on RCTs on the field. My group has a wide collaborative network both nationally and internationally, both in experimental and clinical research. Currently we have active research collaboration with ten national and 22 international (from 13 countries) research groups.

Teaching

Teaching about TBI has been a major part of my work for almost 20 years, both for medical students at the Turku University as well as nationally and internationally. Annually I have about 160 hrs of teaching for medical students.

Research

The research of our TBI has included topics from various disciplines, from psychiatry and neuropsychology to epidemiology, neurosurgery, and biochemistry. During the recent years we have mainly focused in three areas: 1) blood-based brain injury biomarkers, 2) novel brain imaging methodologies, and 3) multifaceted approach to diagnostic and prognostic modeling of TBI. We aim at solving clinical problems and conducting research which is easily transferred to clinical practice. We also collaborate with basic science in order to reveal brain injury mechanisms, since these help in understanding clinical phenomena and in developing new interventions. International collaboration and co-work are an essential part of our research policy.

Publications

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An outlier analysis for acute blood biomarkers of moderate and severe traumatic brain injury (2024)

Journal of Neurotrauma
Korhonen Otto, Mononen Malla, Mohammadian Mehrbod, Tenovuo Olli, Blennow Kaj,Hossain Iftakher, Hutchinson Peter, Maanpää Henna-Riikka, Menon David, Newcombe Virginia, Sanchez Jean-Charles, Takala Riikka, Tallus Riikka, van Gils Mark, Zetterberg Henrik, Posti Jussi
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Predicting recovery in patients with mild traumatic brain injury and a normal CT using serum biomarkers and diffusion tensor imaging (CENTER-TBI) : an observational cohort study (2024)

EClinicalMedicine
Richter, Sophie; Winzeck, Stefan; Correia, Marta M.; Czeiter, Endre; Whitehouse, Daniel; Kornaropoulos, Evgenios N.; Williams, Guy B.; Verheyden, Jan; Das, Tilak; Tenovuo, Olli; Posti, Jussi P.; Vik, Anne; Moen, Kent Gøran; Håberg, Asta K.; Wang, Kevin; Buki, Andras; Maas, Andrew; Steyerberg, Ewout; Menon, David K.; Newcombe, Virginia F.J.; for the CENTER-TBI MRI Substudy Participants and Investigators
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )