Johanna
Lempainen
Docent, Department of Clinical Medicine
Clinical Lecturer, Institute of Biomedicine
Clinical lecturer
Contact
Areas of expertise
pediatrics
pathogenesis of type 1 diabetes
pediatric infections
pediatric immunology
Biography
Docent Johanna Lempainen
graduated from medical school in 2004 (University of Turku) and defended her
PhD theses on pathogenesis of type 1 diabetes in 2009. She received specialist
licence in paediatrics in 2015 and was appointed as a docent of experimental
paediatrics in 2018 (University of Turku). She is currently working as clinical
lecturer at the department of pediatrics at University of Turku and as
specialist at the Unit for Rare Diseases, Turku University Hospital. She
participates in neonatal screening for severe immunodeficiencies and in
laboratory diagnostics of immunodeficiencies. Training for subspecialty in
pediatric infections and immunodeficiencies is ongoing.
Teaching
Docent Lempainen works
as clinical lecturer in pediatrics (part-time) since January 2017.
Research
Docent Lempainen’s
thesis in 2009 focused on the pathogenesis of type 1 diabetes. Since then her
research work has further focused on the heterogeneity of type 1 diabetes
pathogenesis. In 2011 she worked as visiting researcher in the
BabyDiab-diabetes study group in Munich,
Germany. Her current research interests comprise the etiology of beta-cell
autoimmunity in respect of immunological, genetic and epigenetic factors and
disturbances in early microbial contacts and are a part of the prospective
Diabetes Prediction and Prevention (DIPP) study. In addition, she participates
in research projects aiming at early detection of bacterial and viral
infections in infants and children in order to avoid unnecessary antibiotic
exposure. Since January 2020 docent Lempainen is the principal investigator of the Immunogenetics laboratory and PI and member of steering committee in the DIPP study at the University of Turku.
Publications
Heterogeneity in the presentation of clinical type 1 diabetes defined by the level of risk conferred by human leukocyte antigen class II genotypes (2022)
Pediatric Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Comparative analysis of COVID-19 vaccine responses and third booster dose-induced neutralizing antibodies against Delta and Omicron variants (2022)
Nature Communications
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Detection of enterovirus RNA in peripheral blood mononuclear cells correlates with the presence of the predisposing allele of the type 1 diabetes risk gene IFIH1 and with disease stage (2022)
Diabetologia
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Influenza and respiratory syncytial virus during the COVID-19 pandemic: Time for a new paradigm? (2022)
Pediatric Pulmonology
(Kirjoitus tai data-artikkeli tieteellisessä aikakauslehdessä (B1))
Associations between deduced first islet specific autoantibody with sex, age at diagnosis and genetic risk factors in young children with type 1 diabetes (2022)
Pediatric Diabetes
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Non-HLA Gene Polymorphisms in the Pathogenesis of Type 1 Diabetes: Phase and Endotype Specific Effects (2022)
Frontiers in Immunology
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )
Low pre-vaccination SARS-CoV-2 seroprevalence in Finnish health care workers: a prospective cohort study (2022)
Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Strong Neutralizing Antibody Responses to SARS-CoV-2 Variants Following a Single Vaccine Dose in Subjects With Previous SARS-CoV-2 Infection (2022)
Open Forum Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Tri-SNP polymorphism in the intron of HLA-DRA1 affects type 1 diabetes susceptibility in the Finnish population (2021)
Human Immunology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Associations Between IFI44L Gene Variants and Rates of Respiratory Tract Infections During Early Childhood (2021)
Journal of Infectious Diseases
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))