Harry Scheinin profile picture
Harry
Scheinin
Docent, Institute of Biomedicine
Turku PET Centre
MD

Areas of expertise

Anesthesiology
Clinical Pharmacology
Neuroscience
Positron Emission Tomography

Biography

Harry Scheinin leads the Anesthesia Mechanisms Research Group at the University of Turku, Finland, and has studied the human neurobiology of anesthetic agents for 20 years. He has collaborated with Professor Antti Revonsuo since 2005.

Research

We try to explore the neural correlates of human consciousness using, e.g., modern imaging methods. We aim to separate consciousness from responsiveness, connectedness from disconnection and to compare unconsciousness of physiological sleep with that induced by anesthetic agents. Finding new tools for the distinction of consciousness, connectedness and responsiveness would be groundbreaking and could represent a major leap forward in understanding human consciousness. The results could also help in developing new EEG-based methods to objectively measure consciousness and the depth of general anesthesia. 

Publications

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Neuroprotective Effects of Inhaled Xenon Gas on Brain Structural Gray Matter Changes After Out-of-Hospital Cardiac Arrest Evaluated by Morphometric Analysis: A Substudy of the Randomized Xe-Hypotheca Trial (2024)

Neurocritical Care
Hollmén, Carita; Parkkola, Riitta; Vorobyev, Viktor; Saunavaara, Jani; Laitio, Ruut; Arola, Olli; Hynninen, Marja; Bäcklund, Minna; Martola, Juha; Ylikoski, Emmi; Roine, Risto O.; Tiainen, Marjaana; Scheinin, Harry; Maze, Mervyn; Vahlberg, Tero; Laitio, Timo T.
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Response to Letter to the Editor (2023)

Neurogastroenterology and Motility
Cajander Per, Omari Taher, Scheinin Harry, Scheinin Mika, Savilampi Johanna
(Kirjoitus tai data-artikkeli tieteellisessä aikakauslehdessä (B1))

Decreased Thalamic Activity Is a Correlate for Disconnectedness during Anesthesia with Propofol, Dexmedetomidine and Sevoflurane But Not S-Ketamine (2023)

Kantonen Oskari, Laaksonen Lauri, Alkire Michael, Scheinin Annalotta, Långsjö Jaakko, Kallionpää Roosa E., Kaisti Kaike, Radek Linda, Johansson Jarkko, Laitio Timo, Maksimow Anu, Scheinin Joonas, Nyman Mikko, Scheinin Mika, Solin Olof, Vahlberg Tero, Revonsuo Antti, Valli Katja, Scheinin Harry
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Comparison of the prognostic value of early-phase proton magnetic resonance spectroscopy and diffusion tensor imaging with serum neuron-specific enolase at 72 h in comatose survivors of out-of-hospital cardiac arrest-a substudy of the XeHypotheca trial (2022)

Neuroradiology
Koskensalo K, Virtanen S, Saunavaara J, Parkkola R, Laitio R, Arola O, Hynninen M, Silvasti P, Nukarinen E, Martola J, Silvennoinen HM, Tiainen M, Roine RO, Scheinin H, Saraste A, Maze M, Vahlberg T, Laitio TT; XeHYPOTHECA Research Group
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))