Terho Heikkinen profile picture
Terho
Heikkinen
Professor, Paediatrics and Adolescent Medicine
Professor of Paediatrics, MD, PhD
Respiratory infections in children; RESCEU (EU/IMI-funded project 2017-2021); INFORM study

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Areas of expertise

Paediatric infectious diseases
respiratory infections
respiratory viruses
vaccinations
influenza
respiratory syncytial virus
otitis media

Biography

Professor Terho Heikkinen graduated from the Medical School at the University of Turku in 1984, where he also specialized in Paediatrics and Paediatric Infectious Diseases. He defended his thesis on Development and prevention of acute otitis media in children in 1994. Having received the European Society for Paediatric Infectious Diseases Fellowship Award, he worked in 1996-1998 as a post-doc Research Fellow at the University of Texas Medical Branch at Galveston, USA. Subsequently, he worked as a Senior Clinical Researcher and Clinical Lecturer at the Department of Paediatrics, University of Turku. Since 2016, he has been Professor of Paediatrics at the Faculty of Medicine, University of Turku.

During the years, Terho Heikkinen has served as the chairman or a board member of several international and domestic societies in the field of paediatric infectious diseases, including the President of the World Society for Pediatric Infectious Diseases. He is currently a board member of the European Scientific Working Group on Influenza (ESWI), a scientific advisory board and executive committee member of the global Respiratory Syncytial Virus Network (ReSViNET), and the chairman of the Nordic Research Network for Paediatric Infectious Diseases (NORDPID).

Teaching

Since 1999, Terho Heikkinen has worked as a full-time teacher of paediatrics at the Department of Paediatrics, University of Turku. He is also responsible for the organization of the biannual International Course of Paediatrics & Adolescent Medicine for international Erasmus students. He has given 188 invited lectures at various international and domestic academic meetings.


Research

Terho Heikkinen´s major research interest lies in respiratory infections, especially those caused by influenza or respiratory syncytial viruses. In year 2000, he founded his own research group and initiated a long-term research project on respiratory virus infections in children, including the etiology, epidemiology, diagnosis, treatment, prevention, and overall societal impact of these infections and their complications.

Terho Heikkinen has been actively involved in international research collaboration. In 2014, he was a founding member of ReSViNET, a global respiratory syncytial virus research network. He is also a principal investigator in RESCEU (Respiratory syncytial virus consortium in Europe) that in 2017 received 5-year EU/IMI funding for research on the burden of respiratory syncytial virus infections in Europe. He was also a founding member of the Nordic Research Network for Paediatric Infectious Diseases (NORDPID) that was established in 2018.

 

Publications

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Cost-effectiveness of monoclonal antibody and maternal immunization against respiratory syncytial virus (RSV) in infants: Evaluation for six European countries (2023)

Vaccine
Getaneh Abraham M, Li Xiao, Mao Zhuxin, Johannesen Caroline K, Barbieri Eelisa, van Summeren Jojanneke, Wang Xin, Tong Sabine, Baraldi Eugenio, Phijffer Emily, Rizzo Caterina, van Wijhe Maarten, Heikkinen Terho, Bont Louis, Willem Lander, Jit Mark, Beutels Philippe, Bilcke Joke; for Respiratory Syncytial Virus Consortium in Europe (RESCEU) investigators
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

Changes in the global hospitalisation burden of respiratory syncytial virus in young children during the COVID-19 pandemic: a systematic analysis (2023)

Lancet Infectious Diseases
Cong Bingbing, Koç Uğurcan, Bandeira Teresa, Bassat Quique, Bont Louis, Chakhunashvili Giorgi, Cohen Cheryl, Desnoyers Christine, Hammitt Laura L, Heikkinen Terho, Huang Q Sue, Markić Joško, Mira-Iglesias Ainara, Moyes Jocelyn, Nokes D James, Ploin Dominique; VRS study group in Lyon; Seo Euri, Singleton Rosalyn, Wolter Nicole, Fu Yung Chee, Zar Heather J, Feikin Daniel R, Sparrow Erin G; Respiratory Virus Global Epidemiology Network; Nair Harish, Li You; PROMISE investigators
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))

Nirsevimab binding-site conservation in respiratory syncytial virus fusion glycoprotein worldwide between 1956 and 2021: an analysis of observational study sequencing data (2023)

Lancet Infectious Diseases
Wilkins Deidre, Langedijk Annefleur C, Lebbink Robert Jan, Morehouse Christopher, Abram Michael E, Ahani Bahar, Aksyuk Anastasia A, Baraldi Eugenio, Brady Tyler, Tian Chen Albert, Chi Hsin, Choi Eun Hwa, Cohen Robert, Danilenko Daria M, Gopalakrishnan Vancheswaran, Greenough Anne, Heikkinen Terho, Hosoya Mitsuaki, Keller Christian, Kelly Elizabeth J, Kragten-Tabatabaie Leyla, Martinón-Torres Federico, Homero Mascareñas de Los Santos Abiel, Nunes Marta C, Palomino María Angélica, Papenburg Jesse, Pernica Jeffrey M, Richmond Peter, Stein Renato T, Tuffy Kevin M, Verwey Charl, Esser Mark T, Tabor David E, Bont Louis J; INFORM-RSV Study Group
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis (2022)

Lancet
Li Y, Wang X, Blau DM, Caballero MT, Feikin DR, Gill CJ, Madhi SA, Omer SB, Simoes EAF, Campbell H, Pariente AB, Bardach D, Bassat Q, Casalegno JS, Chakhunashvili G, Crawford N, Danilenko D, Ha Do LA, Echavarria M, Gentile A, Gordon A, Heikkinen T, Huang QS, Jullien S, Krishnan A, Lopez EL, Markic J, Mira-Iglesias A, Moore HC, Moyes J, Mwananyanda L, Nokes DJ, Noordeen F, Obodai E, Palani N, Romero C, Salimi V, Satav A, Seo E, Shchomak Z, Singleton R, Stolyarov K, Stoszek SK, von Gottberg A, Wurzel D, Yoshida LM, Yung CF, Zar HJ, Nair H; Respiratory Virus Global Epidemiology Network; Harish Nair 45; RESCEU investigators
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))

Respiratory Syncytial Virus-Associated Hospital Admissions and Bed Days in Children <5 Years of Age in 7 European Countries (2022)

Journal of Infectious Diseases
Wang Xin, Li You, Fernandez Liliana Vazquez, Teirlinck Anne C, Lehtonen Toni, van Wijhe Maarten, Stona Luca, Bangert Mathieu, Reeves Rachel M, Bøås Håkon, van Boven Michiel, Heikkinen Terho, Johannesen Caroline Klint, Baraldi Eugenio, Dona Donà, Tong Sabine, Campbell Harry; Respiratory Syncytial Virus Consortium in Europe (RESCEU) Investigators
(A1 Vertaisarvioitu alkuperäisartikkeli tieteellisessä lehdessä )

The burden of respiratory syncytial virus in healthy term-born infants in Europe: a prospective birth cohort study (2022)

The Lancet Respiratory Medicine
Wildenbeest Joanne G, Billard Marie-Noëlle, Zuurbier Roy P, Korsten Koos, Langedijk Annefleur C, van de Ven Peter M, Snape Matthew D, Drysdale Simon B, Pollard Andrew J, Robinson Hannah, Heikkinen Terho, Cunningham Steve, O'Neill Thomas, Rizkalla Bishoy, Dacosta-Urbieta Ana, Martinón-Torres Federico, van Houten Marlies A, Bont Louis J, RESCEU Investigators
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape (2022)

Lancet Infectious Diseases
Mazur NI, Terstappen J, Baral R, Bardají A, Beutels P, Buchholz UJ, Cohen C, Crowe JE, Cutland CL, Eckert L, Feikin D, Fitzpatrick T, Fong Y, Graham BS, Heikkinen T, Higgins D, Hirve S, Klugman KP, Kragten-Tabatabaie L, Lemey P, Libster R, Löwensteyn Y, Mejias A, Munoz FM, Munywoki PK, Mwananyanda L, Nair H, Nunes MC, Ramilo O, Richmond P, Ruckwardt TJ, Sande C, Srikantiah P, Thacker N, Waldstein KA, Weinberger D, Wildenbeest J, Wiseman D, Zar HJ, Zambon M, Bont L
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))

Age-Specific Estimates of Respiratory Syncytial Virus-Associated Hospitalizations in 6 European Countries: A Time Series Analysis (2022)

Journal of Infectious Diseases
Johannesen Caroline K, van Wijhe Maarten, Tong Sabine, Fernández Liliana V, Heikkinen Terho, van Boven Michiel, Wang Xin, Bøås Håkon, Li You, Campbell Harry, Paget John, Stona Luca, Teirlinck Anne, Lehtonen Toni, Nohynek Hanna, Bangert Mathieu, Fischer Thea K; for the RESCEU Investigators
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
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