Maria
Sundvall
Docent, Institute of Biomedicine
Clinical Lecturer, Institute of Biomedicine
Researcher, Institute of Biomedicine
Senior Researcher, Institute of Biomedicine
MD PhD; Specialist Physician in Clinical Oncology
Areas of expertise
clinical oncology
breast and prostate cancer
targeted cancer therapeutics
cancer biology
cell signaling
posttranslational modifications
dna repair pathways
Biography
Maria Sundvall received her MD degree from the University of Turku in 2003, and defended her PhD thesis at the Department of Medical Biochemistry and Genetics, University of Turku, in 2007. From 2011 she worked nearly 4 years as a postdoctoral fellow in the laboratory of Prof. Pier Paolo Pandolfi, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA. After returning to Finland in 2015 she established her own research group at the University of Turku. Dr. Sundvall received a specialist physician degree in clinical oncology in 2018. Since 2018 Dr. Sundvall has worked as a part-time clinical lecturer at the Institute of Biomedicine, a part-time Academy of Finland clinical researcher and a part-time specialist physician in clinical oncology at Turku University Hospital.
Teaching
Dr. Sundvall has several years of experience in teaching medical students as a clinical lecturer and a university teacher in the fields of medical biochemistry, molecular medicine and cancer during the last 15 years.
Research
Dr. Sundvall has 20 years of experience in studying molecular mechanisms of cancer. Currently she is a principal investigator at University of Turku, and her group is focusing on investigating the role fo DNA repair pathways in prostate cancer. Links:
https://www.utu.fi/en/university/faculty-of-medicine/institute-of-biomedicine/research/cancer-research
https://www.utu.fi/en/university/faculty-of-medicine/institute-of-biomedicine/research/cancer-research
Publications
Function of ERBB4 is determined by alternative splicing. (2011)
Cell Cycle
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
EGFR targeting drugs in the treatment of head and neck squamous cell carcinoma (2010)
Expert Opinion on Emerging Drugs
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))
Cell Death or Survival Promoted by Alternative Isoforms of ErbB4 (2010)
Molecular Biology of the Cell
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Concurrent cetuximab, cisplatin, and radiation for squamous cell carcinoma of the head and neck in vitro (2009)
Radiotherapy and Oncology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Somatic mutations of ErbB4: Selective loss-of-function phenotype affecting signal transduction pathways in cancer (2009)
Journal of Biological Chemistry
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Pim-1 Kinase Expression Predicts Radiation Response in Squamocellular Carcinoma of Head and Neck and Is under the Control of Epidermal Growth Factor Receptor (2009)
Neoplasia : An International Journal for Oncology Research
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Role of ErbB4 in breast cancer (2008)
Journal of Mammary Gland Biology and Neoplasia
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))
Differential nuclear localization and kinase activity of alternative ErbB4 intracellular domains (2007)
Oncogene
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Concomitant chemoirradiation with vinorelbine and gefitinib induces additive effect in head and neck squamous cell carcinoma cell lines in vitro (2007)
Radiotherapy and Oncology
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Association of Wwox with ErbB4 in breast cancer (2007)
Cancer Research
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))