Katri
Lundell
University Teacher, Institute of Biomedicine
FT
Enzyme catalysis
Areas of expertise
Chemistry
Enzyme-catalysed reactions in organic synthesis
Biography
Education:
FM Chemisty 1992
FT Chemistry 2010
Research
We use enzymes as chiral catalysts to get enantiopure compounds. Enantiopurity is important in drug molecules. Substrates are for example alcohols, amino acid esters or amines. We study chemoselectivity and regioselectivity of enzymes as well. Organic solvents are good media for these reactions.
Publications
Nanomolar Protein Thermal Profiling with Modified Cyanine Dyes (2023)
Analytical Chemistry
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))
Advances in the kinetic and dynamic kinetic resolution of piperazine-2-carboxylic acid derivatives with Candida antarctica lipase A; structural requirements for enantioselective N-acylation. (2012)
Arkivoc
(Vertaisarvioitu katsausartikkeli tieteellisessä aikakauslehdessä (A2))
Immobilization to improve the properties of Pseudomonas fluorescens lipase for the kinetic resolution of 3-aryl-3-hydroxy esters. (2012)
Process Biochemistry
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))