Kati Elima profile picture
Kati
Elima
Docent, Faculty of Medicine
Clinical Lecturer, Institute of Biomedicine
InFLAMES Flagship
M.D., Ph.D., Adjunct professor
Molecular mechanisms of cell trafficking; Immunology and cancer biology

Contact

+358 29 450 2325
+358 50 472 5500
Kiinamyllynkatu 10
20520
Turku

Areas of expertise

Molecular mechanisms of cell trafficking
medical education
postgraduate education

Biography

Degrees and competences

- Licenciate of Medicine, 1988, University of Turku, Finland; Doctor of Medical Sciences (M.D., Ph.D.) 1990, University of Turku; Docent in Molecular Medicine, University of Turku.

- Specialist Qualification in Management 2007; General teacher qualification (university pedagogics 60 ECTS), 2014, University of Turku; Special Competence in Medical Education, 2014; Training in practical academic leadership, 2017, TSE

Current tasks

- Clinical lecturer in Molecular Medicine

- Director of Research Track in Molecular Medicine

- Deputy director of Institute of Biomedicine (education)

Previous

- University of Turku: various research and teaching positions at the Department of Medical Biochemistry and Genetics, Faculty of Medicine (assistant, university teacher, clinical lecturer, associate professor, professor)

- National Institute of Health and Welfare: special investigator 

- Academy of Finland: research programme coordinator 

- Turku Graduate School of Biomedical Sciences (TuBS): coordinator 

Teaching

Interest areas:

- Medical education; molecular medicine; genome medicine; 

Teaching responsibilities:

- Medical Biochemistry and Molecular Medicine

- Research Track in Molecular Medicine

- Postgraduate education (doctoral programmes and InFLAMES Flagship)

Other: 

- The Finnish Medical Society Duodecim: Head of education at the Turku region

Research

Lymphatic and vascular endothelium plays a pivotal role in leukocyte and cancer cell migration by expressing counter-receptors for the cell-surface molecules on the migrating cells that mediate trafficking. My research focuses on investigating the molecular mechanisms underlying these interactions and studying the functional role of the individual molecules in various disease processes. Special emphasis is on the roles of the large, multi-domain cell-surface molecule CLEVER-1, and the ecto-enzymes VAP-1 and CD73 in various human cancers.

Publications

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Robo4 contributes to the turnover of Peyer’s patch B cells (2020)

Mucosal Immunology
Fair-Mäkelä Ruth, Ugur Milas, Iftakhar-E-Khuda Imtiaz, Kähäri Laura, Kukkonen-Macchi Anu, Brenyah Heini-Maria, Elima Kati, Miyasaka Masayuki, Pabst Oliver, Jalkanen Sirpa
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Effect of Intravenous Interferon β-1a on Death and Days Free from Mechanical Ventilation among Patients with Moderate to Severe Acute Respiratory Distress Syndrome: A Randomized Clinical Trial (2020)

JAMA: Journal of the American Medical Association
V. Marco Ranieri, Ville Pettilä, Matti K. Karvonen, Juho Jalkanen, Peter Nightingale, David Brealey, Jordi Mancebo, Ricard Ferrer, Alain Mercat, Nicolò Patroniti, Michael Quintel, Jean-Louis Vincent, Marjatta Okkonen, Ferhat Meziani, Giacomo Bellani, Niall MacCallum, Jacques Creteur, Stefan Kluge, Antonio Artigas-Raventos, Mikael Maksimow, Ilse Piippo, Kati Elima, Sirpa Jalkanen, Markku Jalkanen, Geoff Bellingan;
for the INTEREST Study Group
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Fetal-derived macrophages dominate in adult mammary glands (2019)

Nature Communications
Jäppinen N., Félix I., Lokka E., Tyystjärvi S., Pynttäri A., Lahtela T., Gerke H., Elima K., Rantakari P., Salmi M.
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))