Jorma Toppari profile picture
Jorma
Toppari
Professor, Institute of Biomedicine
InFLAMES Flagship
MD, PhD

Contact

+358 29 450 2826
+358 40 180 2600
Kiinamyllynkatu 10
20520
Turku

Areas of expertise

Pediatric endocrinology
reproductive health
endocrine disruption
testis
type 1 diabetes

Biography

Professor Jorma Toppari (H-index 68) is an international expert in environmental endocrine disruption, male reproduction and type 1 diabetes. He is a principal investigator in a NIH-funded cohort study The Environmental Determinants of Diabetes in the Young (TEDDY) and in the Finnish Type 1 Diabetes Prediction and Prevention Study (DIPP). He is leading a joint Finnish-Danish birth cohort study exploring the genetic and environmental aspects of human reproduction. 

Teaching

Basic and clinical endocrinology, particularly pediatric and reproductive endocrinology, endocrine disruption, reproductive toxicology

Research

The aim of our research is to identify risk factors of reproductive health and type 1 diabetes (T1D) to make risk management possible and prevent health problems. We are performing a comprehensive reproductive health study for 19-year-old men that we have followed up prospectively from pregnancy. We focus now our studies on sperm epigenome. We are studying the role of retinoblastoma protein (Rb) and E2F3 transcription factors in gonadal development and whether endocrine disruptors affect reproductive health. In the Finnish type 1 Diabetes Prediction and Prevention (DIPP) study and in The Environmental Determinants of Diabetes in the Young (TEDDY) study we are exploring the early determinants of T1D in large child cohorts with increased genetic risk.

Publications

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[High and increasing prevalence of cryptorchidism in Denmark]. (2004)

Ugeskrift for Laeger
Boisen KA, Kaleva M, Main KM, Virtanen H, Haavisto AM, Schmidt IM, Chellakooty M, Damgaard IN, Mau C, Reunanen M, Skakkebaek NE, Toppari J
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries (2004)

American Journal of Epidemiology
Jensen TK, Jørgensen N, Punab M, Haugen TB, Suominen J, Zilaitiene B, Horte A, Andersen AG, Carlsen E, Magnus Ø, Matulevicius V, Nermoen I, Vierula M, Keiding N, Toppari J, Skakkebaek NE
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))