Ilkka Paatero profile picture
Ilkka
Paatero
Senior Researcher, Turku Bioscience Centre
Ph.D.

Contact

+358 29 450 3789
Tykistökatu 6
20520
Turku

Areas of expertise

cancer
cardiovascular biology
toxicology
microscopy
zebrafish models
model organisms;

Research

My research covers broad range of topics in biomedicine. Current work is dealing mainly with cancer and cardiovascular biology.

My expertise is in application of model organisms, especially zebrafish (Danio rerio), in biomedical research. These models can help to understand and solve biomedical problems efficiently and ethically. Especially, when combined with high-resolution intravital microscopy, these models can give deep insights into developmental and disease processes in vivo. By using fish eggs and embryos, it is also possible to reduce the number of more complex and developed organisms used in research. These models, however, require certain set of skills and knowledge which is not part of the training of most medical and biomedical scientist. To facilite them to utilize the power of zebrafish models to advance their research, I have established a Zebrafish Core under Turku Centre for Biotechnology (University of Turku and Åbo Akademi University).

Publications

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SORLA regulates endosomal trafficking and oncogenic fitness of HER2 (2019)

Nature Communications
Mika Pietilä, Pranshu Sahgal, Emilia Peuhu, Niklas Z. Jäntti, Ilkka Paatero, Elisa Närvä, Hussein Al-Akhrass, Johanna Lilja, Maria Georgiadou, Olav M. Andersen, Artur Padzik, Harri Sihto, Heikki Joensuu, Matias Blomqvist, Irena Saarinen, Peter. J. Boström, Pekka Taimen, Johanna Ivaska
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

GGA2 and RAB13 promote activity-dependent β1-integrin recycling (2019)

Journal of Cell Science
Pranshu Sahgal, Jonna Alanko, Jaroslav Icha, Ilkka Paatero, Hellyeh Hamidi, Antti Arjonen, Mika Pietilä, Anne Rokka, Johanna Ivaska
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))

Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and beta 1-integrin activation (2018)

eLife
Pirita Pekkonen, Sanni Alve, Giuseppe Balistreri, Silvia Gramolelli, Olga Tatti-Bugaeva, Ilkka Paatero, Otso Niiranen, Krista Tuohinto, Nina Perälä, Adewale Taiwo, Nadezhda Zinovkina, Pauliina Repo, Katherine Icay, Johanna Ivaska, Pipsa Saharinen, Sampsa Hautaniemi, Kaisa Lehti, Päivi M Ojala
(Vertaisarvioitu alkuperäisartikkeli tai data-artikkeli tieteellisessä aikakauslehdessä (A1))