Research at the Research Centre of Applied and Preventive Cardiovascular Medicine

Research projects

The Cardiovascular Risk in Young Finns Study (YFS) - Epidemiologic study on atherosclerotic precursors in Finnish children and young adults

The Cardiovascular Risk in Young Finns Study is one of the largest follow-up studies into cardiovascular risk from childhood to adulthood. The main aim is to determine the contribution made by childhood lifestyle, biological, and psychological measures to the risk of cardiovascular diseases in adulthood.

Project Leader: Academy Professor Olli Raitakari

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The STRIP Project - A Prospective Randomized Trial of Atherosclerosis Prevention in Infancy and Childhood - An Epidemiological Study

The STRIP study is unique worldwide; no other study has started dietary intervention in infancy and continued it for 20 years, and simultaneously collected data with repeated measurements on a vast number of risk factors and subclinical markers for cardiovascular health.

The main purpose of the STRIP Study (Special Turku Coronary Risk Factor Intervention Project) is the prevention of atherosclerosis and coronary heart disease by a dietary intervention which began in infancy and has continued to early adulthood. The trial was launched in 1990 when 1062 7-month-old children and their families were enrolled. Half of the families have received individualized dietary and other life-style counseling at least twice a year whereas the rest of the families have served as a control group. The STRIP Study intervention continued until the participants reached the age of 20 years.

Project Leader: Academy Professor Olli Raitakari

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Recent publications of the Research Centre of Applied and Preventive Cardiovascular Medicine

Metabolic syndrome and epigenetic aging: a twin study (2024)

International Journal of Obesity
Föhr Tiina, Hendrix Arne, Kankaanpää Anna, Laakkonen Eija K., Kujala Urho, Pietiläinen Kirsi H., Lehtimäki Terho, Kähönen Mika, Raitakari Olli, Wang Xiaoling, Kaprio Jaakko, Ollikainen Miina, Sillanpää Elina
(Refereed journal article or data article (A1))

Gene expression networks regulated by human personality (2024)

Molecular Psychiatry
del Val Coral, Díaz de la Guardia-Bolívar Elisa, Zwir Igor, Mishra Pashupati P., Mesa Alberto, Salas Ramiro, Poblete Guillermo F., de Erausquin Gabriel, Raitoharju Emma, Kähönen Mika, Raitakari Olli, Keltikangas-Järvinen Liisa, Lehtimäki Terho, Cloninger Claude Robert
(Refereed review article in scientific journal (A2))

Diagnostic Performance of Ultrasonography for Identification of Small Bowel Obstruction: A Systematic Review and Meta-analysis (2024)

Archives of Academic Emergency Medicine
Motavaselian Mohsen, Farrokhi Mehrdad, Khouzani Parisa Jafari, Fard Atousa Moghadam, Daeizadeh Fatemeh, Pourrahimi Mahya, Mehrabani Reyhaneh, Amani-Beni Reza, Farrokhi Masoud, Sarnaghy Faezeh Jalayer, Mir Asal, Tavakoli Reza, Fadavian Heidar, Mehdinezhad Reza, Masoudikabir Parisa, Moallem Maoumeh, Karami Tohid, Roohinezhad Roozbeh, Yazdani Yalda, Ghasemi Didar, Rezaeizadeh Farideh, Hadizadeh Alireza, Sarallah Rojin, Shafigh Ashkan, Aminpour Solmaz, Esfahani Amirhossein, Mirabdali Seyedsaber, Hosseini Zahrasadat, Saharkhiz Farahnaz, Khodsiani Mehrzad, Tirtashi Fahimeh Ebrahimi, Dehkordi Shabnam Esmailian, Amini Nafise Sadat, Aran Mahsa, Abolghasemfard Zohreh, Sanjarinia Nazanin, Abdollahi Zeynab, Abediankenari Fatemeh, Ghadirzadeh Erfan, Khodashenas Mehran, Jahanshahi Ali
(Refereed review article in scientific journal (A2))