Med kuvitus 589

Research at the Institute of Biomedicine

Research at the Institute of Biomedicine is divided into three functional units: 1) Infection and Immunity, 2) Integrative Physiology and Pharmacology and 3) Cancer research. Research at our Institute includes both biomedical basic research and translational research, and the unit division expresses our research priorities.

We encourage creative interdisciplinary combination of research topics via collaboration of the individual research groups and the three units. In addition, we collaborate locally with clinical researchers, with other institutes of our university and with the Åbo Akademi University. We are also widely networked with numerous national and international universities and public and private research institutes.

Research Units

Infection and Immunity (director Cecilia Söderberg-Nauclér)
Integrative Physiology and Pharmacology (director Noora Kotaja)
Cancer Research (director Maria Sundvall)

Research services

Core Facilities of the Institute of Biomedicine

Recent publications

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries (2021)

Nature Communications
Gharahkhani Puya, Jorgenson Eric, Hysi Pirro, Khawaja Anthony P., Pendergrass Sarah, Han Xikun, Ong Jue Sheng, Hewitt Alex W., Segrè Ayellet V., Rouhana John M., Hamel Andrew R., Igo Jr Robert P., Choquet Helene, Qassim Ayub, Josyula Navya S., Bailey Jessica N. Cooke, Bonnemaijer Pieter W. M., Iglesias Adriana, Siggs Owen M., Young Terri L., Vitart Veronique, Thiadens Alberta A. H. J., Karjalainen Juha, Uebe Steffen, Melles Ronald B., Nair K. Saidas, Luben Robert, Simcoe Mark, Amersinghe Nishani, Cree Angela J., Hohn Rene, Poplawski Alicia, Chen Li Jia, Rong Shi-Song, Aung Tin, Eranga Nishanthie Vithana, NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, UK Biobank Eye and Vision Consortium, GIGA study group, 23 and Me Research Team, Tamiya Gen, Shiga Yukihiro, Yamamoto Masayuki, Nakazawa Toru, Currant Hannah, Birney Ewan, Wang Xin, Auton Adam, Lupton Michelle K., Martin Nicholas G., Ashaye Adeyinka, Olawoye Olusola, Williams Susan E., Akafo Stephen, Ramsay Michele, Hashimoto Kazuki, Kamatani Yoichiro, Akiyama Masato, Momozawa Yukihide, Foster Paul J., Khaw Peng T., Morgan James E., Strouthidis Nicholas G., Kraft Peter, Kang Jae H., Pang Chi Pui, Pasutto Francesca, Mitchell Paul, Lotery Andrew J., Palotie Aarno, van Duijn Cornelia, Haines Jonathan L., Hammond Chris, Pasquale Louis R., Klaver Caroline C. W., Hauser Michael, Khor Chiea Chuen, Mackey David A., Kubo Michiaki, Cheng Ching-Yu, Craig Jamie E., MacGregor Stuart, Wiggs Janey L.; FinnGen Study
(Refereed journal article or data article (A1))

Beta cell function in participants with single or multiple islet autoantibodies at baseline in the TEDDY Family Prevention Study: TEFA (2021)

Endocrinology, Diabetes and Metabolism
Martinez Maria Månsson, Salami Falastin, Larsson Helena Elding, Toppari Jorma, Lernmark Åke, Kero Jukka, Veijola Riitta, Koskenniemi Jaakko J., Tossavainen Päivi, Lundgren Markus, Borg Henrik, Katsarou Anastasia, Maziarz Marlena, Törn Carina; The TEDDY Family (TEFA) Study Group
(Refereed journal article or data article (A1))

The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation (2021)

EMBO Reports
El Kharraz Sarah, Dubois Vanessa, van Royen Martin E, Houtsmuller Adriaan B, Pavlova Ekaterina, Atanassova Nina, Nguyen Tien, Voet Arnout, Eerlings Roy, Handle Florian, Prekovic Stefan, Smeets Elien, Moris Lisa, Devlies Wout, Ohlsson Claes, Poutanen Matti, Verstrepen Kevin J, Carmeliet Geert, Launonen Kaisa-Mari, Helminen Laura, Palvimo Jorma J, Libert Claude, Vanderschueren Dirk, Helsen Christine, Claessens Frank
(Refereed journal article or data article (A1))

Recent doctoral dissertations

Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries (2021)

Nature Communications
Gharahkhani Puya, Jorgenson Eric, Hysi Pirro, Khawaja Anthony P., Pendergrass Sarah, Han Xikun, Ong Jue Sheng, Hewitt Alex W., Segrè Ayellet V., Rouhana John M., Hamel Andrew R., Igo Jr Robert P., Choquet Helene, Qassim Ayub, Josyula Navya S., Bailey Jessica N. Cooke, Bonnemaijer Pieter W. M., Iglesias Adriana, Siggs Owen M., Young Terri L., Vitart Veronique, Thiadens Alberta A. H. J., Karjalainen Juha, Uebe Steffen, Melles Ronald B., Nair K. Saidas, Luben Robert, Simcoe Mark, Amersinghe Nishani, Cree Angela J., Hohn Rene, Poplawski Alicia, Chen Li Jia, Rong Shi-Song, Aung Tin, Eranga Nishanthie Vithana, NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, UK Biobank Eye and Vision Consortium, GIGA study group, 23 and Me Research Team, Tamiya Gen, Shiga Yukihiro, Yamamoto Masayuki, Nakazawa Toru, Currant Hannah, Birney Ewan, Wang Xin, Auton Adam, Lupton Michelle K., Martin Nicholas G., Ashaye Adeyinka, Olawoye Olusola, Williams Susan E., Akafo Stephen, Ramsay Michele, Hashimoto Kazuki, Kamatani Yoichiro, Akiyama Masato, Momozawa Yukihide, Foster Paul J., Khaw Peng T., Morgan James E., Strouthidis Nicholas G., Kraft Peter, Kang Jae H., Pang Chi Pui, Pasutto Francesca, Mitchell Paul, Lotery Andrew J., Palotie Aarno, van Duijn Cornelia, Haines Jonathan L., Hammond Chris, Pasquale Louis R., Klaver Caroline C. W., Hauser Michael, Khor Chiea Chuen, Mackey David A., Kubo Michiaki, Cheng Ching-Yu, Craig Jamie E., MacGregor Stuart, Wiggs Janey L.; FinnGen Study
(Refereed journal article or data article (A1))

Beta cell function in participants with single or multiple islet autoantibodies at baseline in the TEDDY Family Prevention Study: TEFA (2021)

Endocrinology, Diabetes and Metabolism
Martinez Maria Månsson, Salami Falastin, Larsson Helena Elding, Toppari Jorma, Lernmark Åke, Kero Jukka, Veijola Riitta, Koskenniemi Jaakko J., Tossavainen Päivi, Lundgren Markus, Borg Henrik, Katsarou Anastasia, Maziarz Marlena, Törn Carina; The TEDDY Family (TEFA) Study Group
(Refereed journal article or data article (A1))

The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation (2021)

EMBO Reports
El Kharraz Sarah, Dubois Vanessa, van Royen Martin E, Houtsmuller Adriaan B, Pavlova Ekaterina, Atanassova Nina, Nguyen Tien, Voet Arnout, Eerlings Roy, Handle Florian, Prekovic Stefan, Smeets Elien, Moris Lisa, Devlies Wout, Ohlsson Claes, Poutanen Matti, Verstrepen Kevin J, Carmeliet Geert, Launonen Kaisa-Mari, Helminen Laura, Palvimo Jorma J, Libert Claude, Vanderschueren Dirk, Helsen Christine, Claessens Frank
(Refereed journal article or data article (A1))
Keywords
Institute of Biomedicine