Med kuvitus 589

Research at the Institute of Biomedicine

Research at the Institute of Biomedicine is divided into three functional units: 1) Infection and Immunity, 2) Integrative Physiology and Pharmacology and 3) Cancer research. Research at our Institute includes both biomedical basic research and translational research, and the unit division expresses our research priorities.

We encourage creative interdisciplinary combination of research topics via collaboration of the individual research groups and the three units. In addition, we collaborate locally with clinical researchers, with other institutes of our university and with the Åbo Akademi University. We are also widely networked with numerous national and international universities and public and private research institutes.

Research Units

Infection and Immunity (director Cecilia Söderberg-Nauclér)
Integrative Physiology and Pharmacology (director Noora Kotaja)
Cancer Research (director Maria Sundvall)

Research services

Core Facilities of the Institute of Biomedicine

Recent publications

The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation (2021)

EMBO Reports
El Kharraz Sarah, Dubois Vanessa, van Royen Martin E, Houtsmuller Adriaan B, Pavlova Ekaterina, Atanassova Nina, Nguyen Tien, Voet Arnout, Eerlings Roy, Handle Florian, Prekovic Stefan, Smeets Elien, Moris Lisa, Devlies Wout, Ohlsson Claes, Poutanen Matti, Verstrepen Kevin J, Carmeliet Geert, Launonen Kaisa-Mari, Helminen Laura, Palvimo Jorma J, Libert Claude, Vanderschueren Dirk, Helsen Christine, Claessens Frank
(Refereed journal article or data article (A1))

Detection of Prostate Cancer Using Biparametric Prostate MRI, Radiomics, and Kallikreins: A Retrospective Multicenter Study of Men With a Clinical Suspicion of Prostate Cancer (2021)

Journal of Magnetic Resonance Imaging
Perez Ileana Montoya, Merisaari Harri, Jambor Ivan, Ettala Otto, Taimen Pekka, Knaapila Juha, Kekki Henna, Khan Ferdhos L, Syrjälä Elise, Steiner Aida, Syvänen Kari T, Verho Janne, Seppänen Marjo, Rannikko Antti, Riikonen Jarno, Mirtti Tuomas, Lamminen Tarja, Saunavaara Jani, Falagario Ugo, Martini Alberto, Pahikkala Tapio, Pettersson Kim, Boström Peter J, Aronen Hannu J
(Refereed journal article or data article (A1))

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer (2021)

Nature Cancer
Qiao YY, Choi JE, Tien JC, Simko SA, Rajendiran T, Vo JN, Delekta AD, Wang LS, Xiao LB, Hodge NB, Desai P, Mendoza S, Juckette K, Xu AL, Soni T, Su FY, Wang R, Cao XH, Yu JL, Kryczek I, Wang XM, Wang XJ, Siddiqui J, Wang Z, Bernard A, Fernandez-Salas E, Navone NM, Ellison SJ, Ding K, Eskelinen EL, Heath EI, Klionsky DJ, Zou WP, Chinnaiyan AM
(Refereed journal article or data article (A1))

Recent doctoral dissertations

The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation (2021)

EMBO Reports
El Kharraz Sarah, Dubois Vanessa, van Royen Martin E, Houtsmuller Adriaan B, Pavlova Ekaterina, Atanassova Nina, Nguyen Tien, Voet Arnout, Eerlings Roy, Handle Florian, Prekovic Stefan, Smeets Elien, Moris Lisa, Devlies Wout, Ohlsson Claes, Poutanen Matti, Verstrepen Kevin J, Carmeliet Geert, Launonen Kaisa-Mari, Helminen Laura, Palvimo Jorma J, Libert Claude, Vanderschueren Dirk, Helsen Christine, Claessens Frank
(Refereed journal article or data article (A1))

Detection of Prostate Cancer Using Biparametric Prostate MRI, Radiomics, and Kallikreins: A Retrospective Multicenter Study of Men With a Clinical Suspicion of Prostate Cancer (2021)

Journal of Magnetic Resonance Imaging
Perez Ileana Montoya, Merisaari Harri, Jambor Ivan, Ettala Otto, Taimen Pekka, Knaapila Juha, Kekki Henna, Khan Ferdhos L, Syrjälä Elise, Steiner Aida, Syvänen Kari T, Verho Janne, Seppänen Marjo, Rannikko Antti, Riikonen Jarno, Mirtti Tuomas, Lamminen Tarja, Saunavaara Jani, Falagario Ugo, Martini Alberto, Pahikkala Tapio, Pettersson Kim, Boström Peter J, Aronen Hannu J
(Refereed journal article or data article (A1))

Autophagy inhibition by targeting PIKfyve potentiates response to immune checkpoint blockade in prostate cancer (2021)

Nature Cancer
Qiao YY, Choi JE, Tien JC, Simko SA, Rajendiran T, Vo JN, Delekta AD, Wang LS, Xiao LB, Hodge NB, Desai P, Mendoza S, Juckette K, Xu AL, Soni T, Su FY, Wang R, Cao XH, Yu JL, Kryczek I, Wang XM, Wang XJ, Siddiqui J, Wang Z, Bernard A, Fernandez-Salas E, Navone NM, Ellison SJ, Ding K, Eskelinen EL, Heath EI, Klionsky DJ, Zou WP, Chinnaiyan AM
(Refereed journal article or data article (A1))
Keywords
Institute of Biomedicine