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Med kuvitus 589

Research at the Institute of Biomedicine

Research at the Institute of Biomedicine is divided into three functional units: 1) Infection and Immunity, 2) Integrative Physiology and Pharmacology and 3) Cancer research. Research at our Institute includes both biomedical basic research and translational research, and the unit division expresses our research priorities.

We encourage creative interdisciplinary combination of research topics via collaboration of the individual research groups and the three units. In addition, we collaborate locally with clinical researchers, with other institutes of our university and with the Åbo Akademi University. We are also widely networked with numerous national and international universities and public and private research institutes.

Research Units

Infection and Immunity (director Cecilia Söderberg-Nauclér)

Integrative Physiology and Pharmacology (director Noora Kotaja)

Cancer Research (director Maria Sundvall)

Research services

Core Facilities of the Institute of Biomedicine

Recent publications

Ovarian Cancers with Low CIP2A Tumor Expression Constitute an APR-246-Sensitive Disease Subtype (2022)

Molecular Cancer Therapeutics

Cvrljevic Anna N. Butt Umar, Huhtinen Kaisa, Grönroos Tove J., Böckelman Camilla, Lassus Heini, Butzow Ralf, Haglund Caj, Kaipio Katja, Arsiola Tiina, Laajala Teemu D., Connolly Denise C, Ristimäki Ari, Carpen Olli, Pouwels Jeroen, Westermarck Jukka

(Refereed journal article or data article (A1))

Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling (2022)

Neurotherapeutics

Hu Wenting, Wang Zhuoqun, Zhang Huiliang, Mahaman Yacoubou Abdoul Razak, Huang Fang, Meng Dongli, Zhou Ying, Wang Shiyi, Jiang Nan, Xiong Jing, Westermarck Jukka, Lu Youming, Wang Jianzhi, Wang Xiaochuan, Shentu Yangping, Liu Rong

(Refereed journal article or data article (A1))

Radium-223 dichloride treatment in metastatic castration-resistant prostate cancer in Finland: A real-world evidence multicenter study (2022)

Cancer Medicine

Hyväkkä A, Kaariainen OS, Utriainen T, Löyttyniemi E, Mattila K, Reinikainen P, Sormunen J, Jääskeläinen M, Auvinen P, Minn H, Sundvall M

(Refereed journal article or data article (A1))

Autoimmune-associated genetics impact probiotic colonization of the infant gut (2022)

Journal of Autoimmunity

Berryman Meghan A, Milletich Patricia L, Petrone Joseph R, Roesch Luiz F, Ilonen Jorma, Triplett Eric W, Ludvigsson Johnny

(Refereed journal article or data article (A1))

A large-scale genomic snapshot of Klebsiella spp. isolates in Northern Italy reveals limited transmission between clinical and non-clinical settings (2022)

Nature Microbiology

Thorpe Harry A., Booton Ross, Kallonen Teemu, Gibbon Marjorie J., Couto Natacha, Passet Virginie, Loez-Fernadez Sebastian, Rodrigues Carla, Matthews Louise, Mitchell Sonia, Reeve Richard, David Sophia, Merla Cristina, Corbella Marta, Ferrari Carolina, Comandatore Francesco, Marone Piero, Brisse Sylvain, Sassera Davide, Corander Jukka, Feil Edward J.

(Refereed journal article or data article (A1))

Recent doctoral dissertations

Ovarian Cancers with Low CIP2A Tumor Expression Constitute an APR-246-Sensitive Disease Subtype (2022)

Molecular Cancer Therapeutics

Cvrljevic Anna N. Butt Umar, Huhtinen Kaisa, Grönroos Tove J., Böckelman Camilla, Lassus Heini, Butzow Ralf, Haglund Caj, Kaipio Katja, Arsiola Tiina, Laajala Teemu D., Connolly Denise C, Ristimäki Ari, Carpen Olli, Pouwels Jeroen, Westermarck Jukka

(Refereed journal article or data article (A1))

Chk1 Inhibition Ameliorates Alzheimer's Disease Pathogenesis and Cognitive Dysfunction Through CIP2A/PP2A Signaling (2022)

Neurotherapeutics

Hu Wenting, Wang Zhuoqun, Zhang Huiliang, Mahaman Yacoubou Abdoul Razak, Huang Fang, Meng Dongli, Zhou Ying, Wang Shiyi, Jiang Nan, Xiong Jing, Westermarck Jukka, Lu Youming, Wang Jianzhi, Wang Xiaochuan, Shentu Yangping, Liu Rong

(Refereed journal article or data article (A1))

Radium-223 dichloride treatment in metastatic castration-resistant prostate cancer in Finland: A real-world evidence multicenter study (2022)

Cancer Medicine

Hyväkkä A, Kaariainen OS, Utriainen T, Löyttyniemi E, Mattila K, Reinikainen P, Sormunen J, Jääskeläinen M, Auvinen P, Minn H, Sundvall M

(Refereed journal article or data article (A1))

Autoimmune-associated genetics impact probiotic colonization of the infant gut (2022)

Journal of Autoimmunity

Berryman Meghan A, Milletich Patricia L, Petrone Joseph R, Roesch Luiz F, Ilonen Jorma, Triplett Eric W, Ludvigsson Johnny

(Refereed journal article or data article (A1))

A large-scale genomic snapshot of Klebsiella spp. isolates in Northern Italy reveals limited transmission between clinical and non-clinical settings (2022)

Nature Microbiology

Thorpe Harry A., Booton Ross, Kallonen Teemu, Gibbon Marjorie J., Couto Natacha, Passet Virginie, Loez-Fernadez Sebastian, Rodrigues Carla, Matthews Louise, Mitchell Sonia, Reeve Richard, David Sophia, Merla Cristina, Corbella Marta, Ferrari Carolina, Comandatore Francesco, Marone Piero, Brisse Sylvain, Sassera Davide, Corander Jukka, Feil Edward J.

(Refereed journal article or data article (A1))

Keywords

Institute of Biomedicine